Application of negative pressure wound therapy after skin grafting in the treatment of skin cancer: A case report.

Background: Skin cancer is a common malignant tumor in dermatology. A large area must be excised to ensure a negative incisal margin on huge frontotemporal skin cancer, and it is difficult to treat the wound. In the past, treatment with skin grafting and pressure dressing was easy to cause complications such as wound infections, subcutaneous effusion, skin necrosis, and contracture.

Effect of positive emotion intervention during late pregnancy on improving colostrum secretion: a randomised control trial protocol.

Introduction: Though evidence has revealed the beneficial effects of cognitive improvement interventions on breastfeeding, the effect of psychological interventions has rarely been studied. This study aims to test whether promoting a positive emotion intervention, 'Three Good Things' intervention, during the last trimester of pregnancy can enhance early colostrum secretion and breastfeeding behaviours by modulating the hormones associated with lactation (prolactin and insulin-like growth factor I). We will attempt to promote exclusive breastfeeding by using physiological behavioural measures.

Vogesella perlucida-induced bacteremia in an advanced-age patient: first case report.

Background: Vogesella species are common aquatic, Gram-negative rod-shaped bacteria, originally described in 1997. Vogesella perlucida was first isolated from spring water in 2008. Furthermore, bacterial pathogenicity of Vogesella perlucida has never been reported.

Role of identified noncoding RNA in erectile dysfunction.

Erectile dysfunction (ED) is a common male sexual dysfunction and is closely related to many risk factors such as age, chronic diseases and mental disorder. Phosphodiesterase type 5 inhibitor (PDE5i) is recommended as the first-line medicine in therapy, but up to 35% of patients fail to this treatment. Unfortunately, the pathogenesis of ED is still poorly understood.

Cryoablation for liver metastasis from solid pseudopapillary tumor of the pancreas: A case report.

Background: Solid pseudopapillary tumor (SPT) of the pancreas is a rare pancreatic tumor and 10% to 15% of cases are associated with metastasis. Cryoablation is a new method that can induce tumor necrosis, and treatment of tumors by cryoablation can cause anti-tumor immune responses.

Case Summary: A 16-year-old woman with SPT of the pancreas developed liver metastases 5.

Irreversible electroporation for liver metastasis from pancreatic cancer: A case report.

Background: Pancreatic cancer has a poor prognosis; 40%-50% of patients have liver metastases at the time of initial diagnosis and only 15%-20% undergo surgical resection. Irreversible electroporation (IRE) is a new, non-thermal local ablation method for solid tumors, which can induce cell membrane permeabilization, resulting in unrecoverable nanoscale perforation and apoptotic cell death without damaging the structural components of tissues.

Case Summary: We report the case of a 66-year-old female patient with liver metastasis from pancreatic cancer with a pathological diagnosis of poorly differentiated adenocarcinoma.

Fate of dissolved organic nitrogen during the Anammox process using ultra-high resolution mass spectrometry.

Anaerobic ammonium oxidation (Anammox) is a cost-effective process for treating highly nitrogenous wastewater. However, the fate of organic nitrogen during Anammox treatment is still unclear, which limits its practical application. In this work, the changes in the quality of dissolved organic nitrogen (DON) in coal liquefaction wastewater (CLW) during Anammox were studied in relation to its chemical composition, which was determined by Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR-MS).

Gender effect of hyperuricemia on the development of nonalcoholic fatty liver disease (NAFLD): A clinical analysis and mechanistic study.

Background And Aims: Hyperuricemia is a risk factor for nonalcoholic fatty liver disease (NAFLD), however, the effect of gender on the hyperuricemia-related NAFLD development remains unclear. Here, we evaluated the clinical characteristics of NAFLD patients with hyperuricemia, and experimentally recapitulated this condition in male rats in order to gain insights on the possible impact of gender on the development of NAFLD in patients with hyperuricemia.

Methods: The clinical characteristics of 238 NAFLD patients, together with the impacts of hyperuricemia on the major parameters related to the development of NALFD were analysed.

Role of identified RNA N6-methyladenosine methylation in liver.

N6-Methyladenosine (mA) is the most abundant and important internal modification site of RNA methylation in viruses and eukaryotic. mA RNA methylation plays key roles in the regulation of post-transcriptional gene expression, including messenger RNA (mRNA), microRNA (miRNA) and long noncoding RNA (lncRNA). And mA methylation regulates the various aspects of RNA metabolism, including structure, maturation, stability, splicing, export, translation and decay.

Roles of Identified Long Noncoding RNA in Diabetic Nephropathy.

Diabetes mellitus is the leading chronic disease in the world, and diabetic nephropathy (DN) as one of its complications could increase the mortality. The development of DN is associated to abnormal hemodynamic factors like cytokine networks and the intervention of metabolic risk factors like blood pressure, blood glucose, and blood lipid. However, the pathogenesis of DN is still poorly understood.

Treating hyperuricemia related non-alcoholic fatty liver disease in rats with resveratrol.

Background Hyperuricemia is a recognised risk factor for the development of nonalcoholic fatty liver disease (NAFLD). This study aims to investigate the therapeutic effect of resveratrol (RES) on the treatment of hyperuricemia-related NAFLD in rats and the underlying mechanisms. Methods NAFLD with hyperuricemia was induced in rats using high-yeast high-fat diet containing potassium oxonate.

[Characteristics of Water Extractable Organic Nitrogen from Erhai Lake Sediment and Its Differences with Other Sources].

The 47 samples from Erhai Lake surface sediments were collected in different seasons. The distribution and structure characteristics of sediment water extractable organic nitrogen(WEON) were investigated by using the combined techniques of UV-Vis absorption and three-dimensional excitation-emission matrix spectra(3DEEMs). The differences in DON of various sources(overlying water, pore water, inflow Rivers and wet deposition) were explored to analyze its effects on sediment.

In-depth molecular characterization and biodegradability of water-extractable organic nitrogen in Erhai Lake sediment.

Dissolved organic nitrogen (DON) constitutes a significant fraction of the total dissolved nitrogen content of most aquatic systems and is thus a major nitrogen source for bacteria and phytoplankton. The present work applied Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) to a compound-level analysis of the depth-dependent molecular composition of water-extractable organic nitrogen (WEON) in lake sediment. The study focused on Erhai Lake, China.

Using combined multiple techniques to characterize refractory organics during anammox process with mature coal chemical wastewater as influent.

This study combined spectroscopy techniques to assess the composition of refractory organics and highlighted the potential application of excitation-emission matrix (EEM) fluorescence spectroscopy within future monitoring of coal chemical wastewater treatment by the anammox process. The results showed that the anammox process could effectively degrade refractory organic substances, with fulvic-like, UV-humic acid, and Vis-humic acid component removal efficiencies of 43.61, 53.

Composition characterization and transformation mechanism of refractory dissolved organic matter from an ANAMMOX reactor fed with mature landfill leachate.

This study applied combined spectroscopy techniques to assess rDOM compositional characteristic and investigated its transformation mechanisms during the treatment of mature landfill leachate by ANAMMOX process. A novel rDOM metabolism mechanism was proposed in this study for the first time. A stable, high nitrogen removal rate of 5.