The metabolic reprogramming of γ-aminobutyrate in oral squamous cell carcinoma.

Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy. The oncometabolites have been studied in OSCC, but the mechanism of metabolic reprogramming remains unclear. To identify the potential metabolic markers to distinguish malignant oral squamous cell carcinoma (OSCC) tissue from adjacent healthy tissue and study the mechanism of metabolic reprogramming in OSCC.

MicroRNA-141-3p inhibits the progression of oral squamous cell carcinoma via targeting PBX1 through the JAK2/STAT3 pathway.

Oral squamous cell carcinoma (OSCC), which is the most common epithelial malignant neoplasm in the head and neck, is characterized by local infiltration and metastasis of lymph nodes. The five-year survival rate of OSCC remains low despite the advances in clinical methods. miR-141-3p has been shown to activate or inhibit tumorigenesis.

A further finite element stress analysis of angled abutments for an implant placed in the anterior maxilla.

To systematically measure and compare the stress distribution on the bone around an implant in the anterior maxilla using angled abutments by means of finite element analysis, three-dimensional finite element simplified patient-specific models and simplified models were created and analyzed. Systematically varied angled abutments were simulated, with angulation ranging from 0° to 60°. The materials in the current study were assumed to be homogenous, linearly elastic, and isotropic.

Angled abutments result in increased or decreased stress on surrounding bone of single-unit dental implants: a finite element analysis.

The influence of angled abutments on stress is a matter of debate. It is widely accepted that increased stress on implants and bone has been associated with the use of angled abutments. However, comparisons of clinical success rates of implants restored with angled and straight abutments indicate no significant differences.

[Treatment of infantile hemangiomas with long pulsed 1064nm laser and oral corticosteroids].

Purpose: To evaluate the clinical therapeutic efficacy on infantile hemangiomas using long pulsed 1064nm laser and oral corticosteroid.

Methods: One hundred and two infantile hemangiomas in the proliferating phase state were treated with long pulsed 1064nm laser, long pulsed 1064nm laser and oral corticosteroid .Color Doppler was used to detect the depth of tumor.

[Clinical analysis of 193 patients with thickening and nodular port wine stains].

Purpose: The purpose of this study is to investigate the relation between age, gender and thickening and nodules in port wine stains(PWS) patients.

Methods: The gender and age of 193 cases with port wine stains were compared between those with flat, those with thickening, those with thickening and nodules, in 0-19, 20-year age group. SAS6012 software package was used for Fisher's exact test and Kruskal-Wallis test.

[Clinical analysis of neurofibromatosis in oral and maxillofacial regions treated with staged operations and laser therapy].

Purpose: To evaluate the clinical effect of neurofibromatosis in the oral and maxillofacial region treated with staged operations and laser therapy.

Methods: Eight cases with neurofibromatosis were treated with staged operations, laser therapy was used for hemostasis during operation, cafe-au-lait was treated with Q-switched laser.

Results: The average amount of bleeding was 100-400 ml, no hemorrhagic shock occurred intraoperatively.

[Thyroid hormone level change in patients undergoing oral and maxillofacial surgery].

Purpose: To study the changes of thyroid hormone level in patients undergoing oral and maxillofacial surgery before and after operation, in order to provide some evidences for postoperative treatment and recovery.

Methods: 60 cases with oral and maxillofacial operations under general or local anesthesia were assayed by radioimmunoassay for hormone levels changes of T3 ,T4, r T3 and TSH in serum before operation and on the first, forth and seventh day after operation. SPSS10.

[Lip and cheek reconstruction with composite radial forearm-palmaris longus tendon flap].

Purpose: To investigate the value of functional reconstruction of the lip and cheek with composite radial forearm-palmaris longus tendon flap.

Methods: Composite radial forearm-palmaris longus tendon flap was used in 5 cases, the flap was folded for repair of oral mucosa and external skin, palmaris longus tendon and the remaining orbicularis muscles were sutured so that oral contour and function could be achieved. All the patients were followed up for at least 20 months.

[Treatment of 113 oral and maxillofacial hemangiomas with long pulsed turnable 1064 nm Gentle YAG laser].

Purpose: To evaluate the clinical therapeutic efficacy on hemangioma of oral maxillofacial regions using pulsed Gentle YAG laser.

Methods: Since April 2005 to August 2005, 113 cases of oral and maxillofacial hemangiomas were treated using pulsed Gentle YAG laser 1064 nm wavelength in our department. Minimal coagulation laser dosage was defined and used to avoid side effects such as thermal skin damage.

[Advances of in vivo confocal scanning laser microscopy].

In vivo confocal scanning laser microscopy is being widely established as a time-saving, non-invasive, investigative methods in the study of body surfaces. Skin can be observed in its native state in vivo without the fixing, sectioning and staining that is necessary for routine histology. It is a new technology that can provide detailed images of tissue architecture and cellular morphology of living tissue.