Publications by authors named "Kebe Obeten"
Article Synopsis
- Fluoxetine (FLX) is a common antidepressant that can negatively affect male fertility by increasing Reactive Oxygen Species (ROS), prompting this study on the protective effects of Vitamin C.
- The study involved treating male Wistar rats with fluoxetine and various doses of Vitamin C over 60 days, measuring their testicular weight, sperm parameters, and oxidative stress markers.
- Results showed that higher doses of Vitamin C improved fertility outcomes, increased antioxidant enzyme levels, and protected testicular structure from FLX damage, indicating its potential as a treatment for drug-induced fertility issues.
Selenium nanoparticles (SeNPs) and metformin (Met) elicit individually protective effects against testicular oxidative injury in diabetic rats. However, the combined effects of both compounds have not been investigated. We investigated the effects of SeNPs and Met individual/co-treatment on testicular oxidative injury in diabetic rats.
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