Publications by authors named "Ke-wei Ji"

Article Synopsis
  • PDAC is a major cause of cancer-related deaths, and despite progress in understanding its causes, treatment outcomes are still unsatisfactory.
  • A meta-analysis was conducted to investigate the link between SMAD4 loss and its clinical implications in PDAC, involving an extensive literature review and data analysis.
  • Results showed a significant increase in SMAD4 protein loss in PDAC compared to nonmalignant tissue, which is associated with poorer overall survival, marking SMAD4 as a potential diagnostic biomarker for PDAC.
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Objective: The aim of this systematic review and meta-analysis is to evaluate the safety and relative benefits of delta-shape anastomosis (DA) by comparing to conventional laparoscopy-assisted distal gastrectomy with Billroth I gastroduodenostomy (LADG BI).

Methods: Studies and relevant literature regarding DA versus LADG BI were searched in the electronic databases. Operation time, postoperative complications, estimated blood loss, number of retrieved lymph nodes, time to first flatus, time to oral intake, length of postoperative hospitalization in DA and LADG BI were pooled and compared using meta-analysis.

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Bruton's tyrosine kinase (Btk) is a member of the Tec-family non-receptor tyrosine kinases family. It has previously been reported to be expressed in B cells and has an important role in B-cell malignancies. While the roles of Btk in the pathogenesis of certain B-cell malignancies are well established, the functions of Btk in gastric carcinoma have never been investigated.

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Background: Recently, microRNA-21 (miR-21) has been reported to be associated with prognosis of pancreatic ductal adenocarcinoma (PDAC). The present studies aimed to evaluate the prognostic value of miR-21 for PDAC with meta-analysis.

Methods: A systematic search in the PubMed and other databases was conducted to identify eligible studies.

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Objective: To investigate the clinical effect of laparoscopic-assisted radical distal resection of invasive gastric cancer.

Methods: Forty-seven patients with advanced gastric cancer, 33 males and 14 females, aged 58.2 (36 - 77), underwent laparoscopic-assisted radical resection and then were followed up for 17 months (2 - 33 months).

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