Optimization of ultrasonic-assisted extraction of total flavonoids from by a hybrid response surface methodology-artificial neural network-genetic algorithm (RSM-ANN-GA) approach, coupled with an assessment of antioxidant activities.

The objective of this research endeavor is to refine the ultrasonic-assisted extraction technique for total flavonoids from (TFO), utilizing a synergistic approach combining response surface methodology (RSM) and artificial neural network integrated with genetic algorithm (RSM-ANN-GA). The optimized extraction parameters determined through RSM yielded a TFO concentration of 13.538 mg g under the following conditions: an ethanol concentration of 61.

Application of anatomy unit resection surgery for lateral basicranial surgical approach in oral squamous carcinoma.

Background: The basicranial region lacks definite boundaries and includes various anatomical units. We developed a novel concept of the posterior oral anatomical complex (POAC) to identify these anatomical units in the basicranial region. OSCC with POAC involvement is termed posterior oral squamous cell carcinoma (POSCC) with poor prognosis.

[In vitro anti-Trichomonas vaginalis effects of a mixture of dihydroartemisinin and metronidazole].

Objective: To observe the effect of a mixture of dihydroartemisinin and metronidazole on ultrastructure of Trichomonas vaginalis trophozoites in vitro for exploring trichomonacidal mechanism of the drug mixture.

Methods: The trophozoites were cultivated with liver extract solution medium that contained 2.5 x 10(6) parasites/ml.

[Phytochemical and pharmacological research progress in Tussilago farfara].

Tussilago farfara contained the chemical constitutents including terpenes, flavonoids, and alkanoids. It has been used for the relief of coughs and as an expectorant, blood pressure raiser, platelet activating factor inhibitor and anti-inflammatory agents. This paper reviewed the phytochemical and pharmacological research progress in T.

4-(4-Nitro-benzene-sulfonamido)pyridinium trichloro-acetate.

In the title compound, C(11)H(10)N(3)O(4)S(+)·C(2)Cl(3)O(2) (-), the benzene ring forms an angle of 85.21 (13)° with the pyridinium ring. The nitro group is nearly coplanar with its attached benzene ring [dihedral angle = 3.