Safety and Efficacy of Hydrogen Peroxide in Controlling Blood Loss and Surgical Site Infection After Multisegmental Lumbar Spine Surgery: A Retrospective, Case-Controlled Study.

Objective: To explore the safety and efficacy of hydrogen peroxide HO in controlling blood loss and surgical site infection (SSI) after multisegmental lumbar spine surgery.

Methods: A total of 2626 patients who had undergone multisegmental lumbar spinal surgery from January 2015 to January 2018 were included in the present study. Stratified by the use of HO irrigation, they were divided into 2 groups: the control group (n = 1345) and the experimental group (n = 1281).