Publications by authors named "Ke-Yong Bao"
Article Synopsis
- EZH2 is a key enzyme that influences gene expression by modifying histones and is linked to resistance to anoikis, a process that prevents detached cells from surviving, which is important in ovarian adenocarcinoma metastasis.
- The study involved analyzing EZH2 levels in ovarian cancer tissues and using models to assess how altering EZH2 and m6A (a specific RNA modification) affects cancer cell survival and progression.
- Findings show that higher EZH2 levels are associated with increased anoikis resistance in ovarian cancer, suggesting that targeting EZH2 and m6A could be promising strategies for treating patients with ovarian cancer.
