Publications by authors named "Ke-Xiang Yu"
H5N1 and H9N2 viruses are important causes of avian influenza in China. H5N1 is typically associated with severe to fatal disease in poultry, while H9N2 is usually associated with mild disease. Differences in viral virulence prompted us to investigate whether innate immune responses would be differentially regulated following infection by H5N1 and H9N2 viruses.
View Article and Find Full Text PDFArticle Synopsis
- * Phylogenetic analysis reveals that the H4N6 virus is of Eurasian lineage and likely resulted from a reassortment involving other avian viruses, indicating it has features of low-pathogenic avian influenza viruses.
- * Findings suggest the virus is unlikely to infect mammals, including humans, due to specific genomic traits and low antibody prevalence in duck serum samples, hinting at an alternative reservoir for the virus.
The goal of this study is to research the genetic characteristics and relationship between HN and P genes of NDV. The nucleotide sequence and deduced amino acid sequence were analyzed for the Hemagglutinin-neuramindase (HN) and Phosphoprotein (P) gene of twelve field isolates of Newcastle disease virus (NDV) during 1997-2005 in China. The HN and P gene sequences of fifteen NDV reference strains from GenBank were also used in this study.
View Article and Find Full Text PDF