Publications by authors named "Ke-Wei Pan"
Article Synopsis
- - Nuclear dysmorphia, which refers to abnormal nuclear shapes in cancer cells, is linked to cancer severity and is characterized by irregular nuclear formations, with vimentin being a key protein involved in this process.
- - In breast cancer cells (MDA-MB-231), vimentin intermediate filaments were found to accumulate at the concave areas of dysmorphic nuclei, and removing vimentin helped restore the nuclear shape, unlike a mutant form that couldn't assemble correctly.
- - The study also revealed that depleting vimentin in lung cancer cells (A549) reduced nuclear dysmorphia during a process induced by TGFβ and associated with further DNA repair defects, indicating vimentin's
Monolithic phosphor-free two-color gallium nitride (GaN)-based white light emitting diodes (LED) have the potential to replace current phosphor-based GaN white LEDs due to their low cost and long life cycle. Unfortunately, the growth of high indium content indium gallium nitride (InGaN)/GaN quantum dot and reported LED's color rendering index (CRI) are still problematic. Here, we use flip-chip technology to fabricate an upside down monolithic two-color phosphor-free LED with four grown layers of high indium quantum dots on top of the three grown layers of lower indium quantum wells separated by a GaN tunneling barrier layer.
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