Publications by authors named "Ke-Ling Zhang"
Background: Cortical spreading depression can cause migraine attack, and up-regulate matrix metalloproteinase-9 (MMP-9) expression in animal. This study aimed to determine the impact on the structure and function of the blood-brain barrier by measuring plasma MMP-9 levels in patients at the acute and late stages of migraine attacks in order to elucidate the pathological mechanisms involved.
Methods: We recruited a case-control cohort of 38 adult migraine patients and 20 age- and gender-matched healthy control subjects.