ZYGOTE-ARREST 3 that encodes the tRNA ligase is essential for zygote division in Arabidopsis.

In sexual organisms, division of the zygote initiates a new life cycle. Although several genes involved in zygote division are known in plants, how the zygote is activated to start embryogenesis has remained elusive. Here, we showed that a mutation in ZYGOTE-ARREST 3 (ZYG3) in Arabidopsis led to a tight zygote-lethal phenotype.

Expressed genes in regenerating rat liver after partial hepatectomy.

Aim: To reveal the liver regeneration (LR) and its control as well as the occurrence of liver disease and to study the gene expression profiles of 551 genes after partial hepatectomy (PH) in regenerating rat livers.

Methods: Five hundred and fifty-one expressed sequence tags screened by suppression subtractive hybridization were made into an in-house cDNA microarray, and the expressive genes and their expressive profiles in regenerating rat livers were analyzed by microarray and bioinformatics.

Results: Three hundred of the analyzed 551 genes were up- or downregulated more than twofolds at one or more time points during LR.

Identification of expressed genes in regenerating rat liver in 0-4-8-12 h short interval successive partial hepatectomy.

Aim: To identify the genes differentially expressed in the regenerating rat liver of 0-4-8-12 h short interval successive partial hepatectomy (SISPH) and to analyze their expression profiles.

Methods: Five hundred and fifty-one elements screened from subtractive cDNA libraries were made into a cDNA microarray (cDNA chip). Extensive gene expression analysis following 0-4-8-12 h SISPH was conducted by microarray.

Gene expression differences of regenerating rat liver in a short interval successive partial hepatectomy.

Aim: To identify the genes expressed differentially in the regenerating rat liver in a short interval successive partial hepatectomy (SISPH), and to analyze their expression profiles.

Methods: Five hundred and fifty-one elements selected from subtractive cDNA libraries were conformed to a cDNA microarray (cDNA chip). An extensive gene expression analysis following 0-36-72-96-144 h SISPH was performed by microarray.

[The origination and action of the hepatic stems cells].

Oval cells are small cells with scant cytoplasm and ovoid-shaped nuclei. These cells, probably deriving from the bone marrow or the cell population associated with the bone marrow, are activated hepatic stem cell. The morphological characteristic of the hepatic stem cells is similar to the oval cells and its biochemistry marker is c-kit/CD45/TRE19.