Publications by authors named "Ke-Ji Li"

Objective: This study aimed to measure the basal energy expenditure (BEE) of Chinese healthy adults and establish an accurate predictive equation for this population.

Methods: In total, 470 Chinese healthy adults had their BEE measured using the Cosmed K4b portable metabolic system. Multiple linear regression analysis was applied to develop new optimal equations for predicting BEE.

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Background: Gastric cancer is one of the most common and deadly malignancies worldwide. Despite recent medical progress, the 5-year survival rate of gastric cancer is still unsatisfactory. 5-fluorouracil (5-Fu) is one of the first-line antineoplastic treatments for gastric cancer, as it can effectively induce cancer cell apoptosis.

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To investigate the metabolic differences of calcium requirements between Chinese and Westerners, we examined systematically the characteristics of calcium metabolism in Chinese adults with habitual dietary calcium intakes. We searched PubMed, Cochrane Library, SinoMed, and National Index to Chinese Newspapers & Periodicals, from inception to March 17, 2015, as well as the bibliographies of any relevant papers and journals, for trials assessing calcium metabolism in healthy Chinese adults within 18-60 years of age on the typical Chinese diet. We extracted a standardized dataset from metabolic studies that reported intake, retention, urinary excretion, faecal excretion and/or fractional absorption of calcium.

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Introduction: MicroRNAs (miRNAs) are non-coding RNAs that regulate multiple cell processes during cancer progression. Renal cell carcinoma (RCC) is a malignancy with a poor prognosis. In this study, we aimed to investigate the roles of miR-630 in RCC progression.

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Article Synopsis
  • miR-630 is a noncoding RNA linked to cancer progression and is found to be upregulated in clear cell renal cell carcinoma (ccRCC) for the first time.
  • Its expression levels were significantly higher in tumor tissues compared to normal tissues in a study of 92 ccRCC patients.
  • High levels of miR-630 correlate with poor patient prognosis and serve as an independent prognostic marker, suggesting it could be a valuable biomarker for ccRCC.
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Objective: To examine the association of visceral adiposity as measured by VFA and WC with lipid and glucose metabolic biomarkers in abdominally obese Chinese adults, and to assess whether WC could be an indicator of visceral fat.

Methods: WC and VFA were measured in 155 overweight and obese adults. A fasting blood sample was collected from participant (n = 118) whose VFA > or = 100 cm2 for analyses of lipid and glucose profile.

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  • A μ-SPE device utilizing copper(II) isonicotinate was created to efficiently extract and analyze PBDEs from soil samples through gas chromatography with a micro-cell electron capture detector.
  • Various extraction variables, such as temperature and time, were optimized to achieve low detection limits for seven PBDEs, indicating high sensitivity and good reproducibility of the method.
  • The method demonstrated recovery rates of 70-90% for PBDEs, showing it as an effective alternative for detecting these contaminants in field-contaminated soils.
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Objective: The purpose of this study was to explore how obesity was covered in television news in China, including the trends over time and the characteristics of obesity-related news.

Methods: The frame analysis was adopted to assess the content of obesity-related news broadcasted in China Central Television (CCTV) from 1982 to 2009. To investigate the characteristics of the news, the obesity-related news was divided into subgroups according to populations concerned, as well as the period in which the news was broadcasted.

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  • Consumption of resistant starch (RS)-enriched rice reduces post-meal blood glucose and insulin levels compared to wild-type rice, showing significant improvements in glycaemic index (GI) and insulin index (II).
  • In a study involving sixteen young Chinese adults, the effects of RS rice were assessed against glucose and wild-type rice using a crossover design with a washout period.
  • The intake of RS rice led to higher production of H2 gas in the breath after meals, indicating increased fermentation in the large intestine, while also maintaining similar fasting blood glucose and insulin levels.
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Objective: This study examined whether the two polymorphisms of GPX1 (198Pro--> Leu) and TXNRD2 (370Lys-->Arg) contributed alone or in combination, to the risk of gastric cancer development.

Methods: A total of 361 patients with gastric cancer and 363 cancer-free controls were recruited and their genotypes of the two polymorphisms were determined by polymerase chain reaction-based restrictive fragment length polymorphism (PCR-RFLP) method. Odds ratio (OR) and 95% confidence interval (CI) were computed using unconditional logistic regression model.

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  • The study investigates the link between visceral fat, pulse-wave velocity (PWV), and endothelial dysfunction in peritoneal dialysis (PD) patients, highlighting the ongoing debate about the impact of obesity on mortality in this group.
  • Bivariate correlation showed that higher visceral fat levels are associated with increased PWV and decreased flow-mediated dilation (FMD), indicating worse cardiovascular health.
  • The findings suggest visceral fat is a significant independent predictor of both PWV and FMD, pointing to its potential role as a cardiovascular disease risk factor in PD patients.
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Objective: Using accelerometer and physical activity logs to evaluate daily energy expenditure, as to providing a simple and convenient method to survey the total energy expenditure (TEE).

Methods: The different activity intensities recorded by accelerometer were distinguished into a certain different energy expenditure value by gas metabolism method. Forty-one participants wore the accelerometer for 7 days continuously and completed physical activity logs everyday at the same time.

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Objective: To study the reliability and validity of Chinese version of International Physical Activity Questionnaire (IPAQ) and to provide an instrument for physical activity measurement in Chinese-spoken population.

Methods: Test-retest reliability was systemically assessed in 94 participants sampled from college students. Questionnaires were completed twice with a three-day interval.

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