Publications by authors named "Ke-Cheng Lu"

RNA interference (RNAi) is a conservative and important functional pathway in eukaryocyte. It regulates the expression of genes that are engaged in a variety of cellular physiological functions. Among the functions of RNAi, its antiviral function have attracted many attentions.

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Article Synopsis
  • - The study investigates the impact of endoplasmic reticulum (ER) stress on the health of the whiteleg shrimp (Litopenaeus vannamei), highlighting its role in aquatic animal diseases and the need for a better understanding of environmental stress responses.
  • - Using RNA-Seq technology, researchers found significant changes in gene expression, with 286 genes upregulated and 473 downregulated when shrimp were treated with Thapsigargin, indicating the activation of the ER-stress response.
  • - The findings suggest that ER-stress affects immune-related genes, particularly Prophenoloxidase activating enzyme 2 (LvPPAE2), which plays a role in shrimp's defense against pathogens, providing insights into how shrimp
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The interplay between virus and host has been one of the hot spot in virology, and it is also the important aspect of revealing the mechanism of virus infection. Increasing studies revealed that several key molecules took part in the process of virus-host interaction. White spot syndrome virus (WSSV) has been proved to affect several physiological processes of the host cells, especially apoptosis.

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Seeking out fish meal (FM) alternatives is an important requirement for aquaculture all over the world. And most practitioners believe that the plant protein is most potential for FM surrenal. While high plant protein feed caused some common problems in aquatic livestock: the absorption rate and growth rate are decreased, and even caused digestive tract inflammation.

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Cell survival is based on the stability of intracellular state. It was well known that biochemical reactions in cells require specific intracellular environments, such as pH and calcium concentration. While the mechanism of stabilizing the intracellular environment is complex and far from clear.

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Article Synopsis
  • * LvTRIM32 is predominantly expressed in certain tissues like hemocytes, gills, and epidermis, and exhibits E3 ubiquitin ligase activity, playing a role in shrimp's response to oxidative stress and infections.
  • * The findings suggest that LvTRIM32 enhances shrimp resistance to oxidative stress and infections from the white spot syndrome virus (WSSV) and Vibrio alginolyticus, highlighting its significance in the shrimp antioxidant stress system.
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C-type lectins (CTLs), which bind carbohydrates in a Ca-dependent manner, are involved in many cellular activities, especially immunity. CTLs play important roles in both the antibacterial and the antiviral immune response and are also associated with autoimmunity. Several CTLs have been investigated in crustaceans, primarily with respect to their function in the immune response.

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An all-single-mode-fiber L-band superfluorescent fiber source (SFS) with 1 W output power, 34.3 nm bandwidth (FWHM) and 54% optical conversion efficiency is constructed by seeding a high power erbium-doped fiber amplifier (EDFA) with a low power L-band ASE seed source to avoid parasitic lasing. The source is resonantly pumped by a high power C-band SFS peaked at 1545 nm.

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A branch arm filtering technique is firstly proposed and experimentally demonstrated. A tunable band pass filter is inserted into one branch arm of the Mach-Zehnder type resonator instead of into the common arm as usual, in the coherent combining of two tunable fiber lasers. The arrangement improves the efficiency of the laser without obvious spectral quality penalty.

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An L band superfluorescent fiber source (SFS) with output power of 0.94W is presented, under 4.4W 976nm pump power.

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A cw laser-diode-pumped Yb-doped double-clad fiber laser operating in a hybrid Q-switched regime was demonstrated. The output pulses had a duration as short as 4.2 ns, a tunable wavelength range from 1080.

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A laser-diode-pumped Yb-doped double-clad fiber laser operating in a hybrid Q-switched regime has been demonstrated. With pulsed pump light and stimulated Brillouin scattering of the gain fiber as the Q-switching mechanisms, the laser generated nanosecond pulses with a stable repetition rate. A single-pulse energy of as much as 143.

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