Publications by authors named "Ke-Bin Zeng"
Background: Edaravone is a widely used treatment for patients with cerebral infarction and, in most cases, edaravone-induced side effects are mild. However, edaravone-related adverse reactions have been receiving increasing attention.
Case Summary: We treated three patients with acute cerebral infarction who died following treatment with edaravone.
Article Synopsis
- ERK1/2 is phosphorylated and activated during environmental stress, like epileptiform discharge, influencing abnormal axon growth and synapse changes in neurons.
- Neurons were tested in a controlled environment without magnesium, and the effects of the ERK1/2 inhibitor U0126 were compared at various time points following discharge.
- The presence of phosphorylated ERK1/2, C-fos, GAP-43, and synaptophysin increased together after discharge, while inhibition of ERK1/2 led to a reduction in these markers, suggesting ERK1/2's role in promoting changes related to epilepsy.
[Excitatory characteristics of glutamate on hippocampus neurons cultured in vitro].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
November 2005