Tongue squamous cell carcinoma (SCC) is associated with a high likelihood of cervical lymph node metastasis (CLNM), leading to a poor prognosis.
A study of 89 patients focused on identifying clinicopathological features that predict CLNM in early-stage tongue SCC, using methods like Kaplan-Meier survival analysis and Cox regression.
Significant risk factors for CLNM included clinical stage T2, depth of invasion greater than 5 mm, tumor budding, and high-grade differentiation, with about 25.8% of patients exhibiting CLNM, indicating the need for close monitoring in at-risk patients post-surgery.