Brain-Derived Extracellular Matrix (B-ECM)-Based Aligned Electrospun Fibers for Sciatic Nerve Regeneration.

Nerve injuries pose numerous challenges and adversely affect the quality-of-life (QOL) of patients. Artificial nerve guidance conduits (aNGCs) are fabricated using natural and synthetic polymers alongside bioactive cues. The objective of this study is to simultaneously leverage biophysical and biochemical cues to develop aNGCs.