The Structure of Human Sebaceous Glands and Its Relation to Skin Viscoelasticity.

High-frequency ultrasound has realized high-resolution observation of deep part of the dermis in vivo. The size of sebaceous glands was evaluated by three-dimensional ultrasound microscopy with the ultrasonic frequency of 120 MHz. The viscoelasticity of the same regions was measured by well-established biomechanical equipment.

High-resolution ultrasound imaging of human skin in vivo by using three-dimensional ultrasound microscopy.

Observing the morphology of human skin is important in the diagnosis of skin cancer and inflammation and in the assessment of skin aging. High-frequency ultrasound imaging provides high spatial resolution of the deep layers of the skin, which cannot be visualized by optical methods. The objectives of the present study were to develop a three-dimensional (3-D) ultrasound microscope and to observe the morphology of normal human skin in vivo.

Imaging of sebaceous glands of human skin by three-dimensional ultrasound microscopy and its relation to elasticity.

High frequency ultrasound imaging has realized high resolution in vivo imaging of the biological tissues at a microscopic level. Human skin structure, especially sebaceous glands at the deep part of the dermis, was observed by three-dimensional ultrasound microscopy with the central frequency of 120 MHz. The visco-elasticity and surface sebum level of the observed region were measured by established testing devices.