Effects of S-PRG eluate on oral biofilm and oral malodor.

Objectives: This study evaluated the effects of a surface pre-reacted glass-ionomer (S-PRG) eluate on oral microbiota and dental biofilms in vitro, and on oral malodor and tongue bacterial loads clinically.

Study Design: The effect of S-PRG eluate on the growth and survival of salivary bacteria was examined under both aerobic and anaerobic conditions; its ability to inhibit new biofilm formation and disrupt mature biofilms was also evaluated. The concentration of volatile sulfur compounds (VSCs) was measured using a portable sulfide monitor before and after rinsing with S-PRG eluate or distilled water.