Use of tricyclic antidepressants as analgesic adjuvants results in nonhazardous prolongation of the QTc interval.

Background: Tricyclic antidepressants (TCAs) are known to prolong QTc interval. However, little is known about the QTc lengthening effect of TCAs at analgesic dosages and the predictive factors for abnormal QTc prolongation.

Methods: We conducted a single-center, retrospective observational study, and evaluated 87 patients (65 amitriptyline, 22 nortriptyline) who underwent 12-lead electrocardiogram (ECG) examinations both before and after receiving TCAs for herpes zoster pain or postherpetic neuralgia from May 2007 to January 2012.

The impact of intraoperative hypothermia on early postoperative adverse events after radical esophagectomy for cancer: a retrospective cohort study.

Objective: To investigate the correlation between intraoperative body temperature and postoperative adverse effects in patients who underwent esophagectomy procedures.

Design: Retrospective cohort study.

Setting: University Hospital.

[Introduction of hospital information system and anesthesia information management system into the perianesthetic practice at Osaka City University Hospital].

Background: Recently, the hospital information systems (HIS) and anesthesia information management systems (AIMS) have been rapidly improved and have been introduced into the clinical practice in Japan drastically; however, few reports have detailed their influences on clinical practice. We here report our experience.

Methods: We introduced HIS (EGMAIN-EX, Fujitsu Co.