Publications by authors named "Kazutaka Nakao"
Cortical blindness (CB) due to contrast-induced encephalopathy is a rare complication in endovascular procedure. Although exact mechanism is not known, disruption of blood-brain barrier (BBB) by contrast agent is supposed to be caused. We report two cases of contrast-induced encephalopathies after coil embolization of unruptured aneurysm.
View Article and Find Full Text PDFBackground: The prevalence of unruptured intracranial aneurysms is increasing in elderly population in Japan. Octogenarians (80-89 years) are more prone to complications due to increased age, comorbidities, increased risk of vasospasm, and treatment risks.
Aim: The aim is to study the surgical outcome of unruptured intracranial saccular aneurysms in elderly patients aged between 80 and 89 years.
Background: Extracranial-intracranial (EC-IC) arterial bypass has been used in the treatment of various cerebrovascular ischemic disease due to atherosclerosis or Moyamoya disease, skull base tumors encasing large IC artery or complex IC aneurysms.
Aim: The aim is to analyze surgical technique (EC-IC bypass) and its outcome with intraoperative use of dual image video angiography (DIVA) and Doppler ultrasound.
Materials And Methods: We studied in this article a series of 23 patients operated in Banbuntane Hotokukai Hospital, Fujita Health University, for which a superficial temporal artery-middle cerebral artery anastomosis was done for steno-occlusive disease, giant IC aneurysm or Moyamoya disease.
Background/aim: Temozolomide (TMZ) induces prolonged arrest of human glioma cells in the G/M phase and inhibition of the G checkpoint intensifies the effect of TMZ. These findings suggest that the G checkpoint is linked to DNA repair mechanisms.
Materials And Methods: To clarify the mechanism of TMZ resistance, we established TMZ-resistant (TR) clones by serial treatment of U87MG cells with TMZ.