Henoch-Schönlein Nephritis Manifesting with Purpura 15 years after Diagnosis of IgA Nephropathy.

Henoch-Schönlein nephritis or immunoglobulin A (IgA) vasculitis is characterized by purpura, arthralgia, abdominal pain, and glomerulonephritis with glomerular IgA deposition. Notably, the presence of purpura is essential to diagnose this disease. We report the case of a patient in whom proteinuria and haematuria were detected during screening tests and he was diagnosed with IgA nephropathy at 20 years of age.

Incontinentia pigmenti in a male (XY) infant with long-term follow up over 8 years.

Incontinentia pigmenti (IP) is an X-linked genodermatosis affecting the skin and other sites, including the teeth, nails, hair, eyes and nervous system defects in female patients. Generally lethal in males, there are only a few known cases of males surviving this condition. Nuclear factor (NF)-κB essential modulator (NEMO), also known as inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma (IKBKG), constitutes an essential activator of NF-κB.

Novel SLC39A4 mutations in acrodermatitis enteropathica.

Acrodermatitis enteropathica is an autosomal recessive disease characterized by skin involvement due to defective intestinal zinc absorption. Usually, the skin lesions include erythema, erosions, and small blisters in perioral, perianal regions, and hands and feet, which develop soon after weaning from the breast. The acrodermatitis enteropathica gene has been localized to chromosomal region 8q24.

A dynamic method of measuring surface potential change due to binding of bitter substance at monolayer-coated liquid membrane surface.

A dynamic method of determining the membrane surface potential change due to a binding of a hydrophobic ion has been presented. The surface potential was determined from the time course of membrane potential under zero electric current during a transition between two steady states in a membrane filter impregnated with a phospholipid and 1-octanol. One of the alkaloids, quinine hydrochloride, was used as a hydrophobic electrolyte.