Publications by authors named "Kazumasa Nagai"

Article Synopsis
  • Replacing a lumen-apposing metal stent (LAMS) with a double-pigtail plastic stent (DPS) is effective for preventing recurrence of walled-off necrosis, but traditional success rates are low; so a new technique was developed.
  • In the new method, a 7-F DPS is placed inside the LAMS to facilitate its removal while allowing granulation to occur, which stabilizes the DPS; out of 18 patients, 17 had successful replacements with no recurrences observed over 385 days.
  • Prior to this technique, replacing LAMS with DPS had a low success rate (61.8%), and recurrence of pancreatic fluid collection was noted in 15.3% of patients who could
View Article and Find Full Text PDF
Article Synopsis
  • * The procedure took an average of 27.3 minutes, with significant improvement in GOO symptoms over time, achieving an overall survival rate of about 194 days post-procedure.
  • * While EPASS had a 16.2% rate of mild adverse events, it maintained 100% stent patency, emphasizing its safety and reliability for managing malignant GOO cases.
View Article and Find Full Text PDF

Tract dilation prior to stent placement is an important step in endoscopic ultrasound-guided hepaticogastrostomy. Mukai and colleagues describe their use of a novel catheter with a longer balloon, which enables one-step tract dilation of the gastric wall, liver parenchyma, and bile duct wall, shortening the procedure and reducing bile leakage.

View Article and Find Full Text PDF

Background: Endoscopic papillectomy (EP) is less invasive than surgery but procedure-related adverse events (AEs) still frequently occur. This study compared the benefits of EP using a new optimal endoCUT setting on the VIO (Erbe) electrosurgical unit (VIO-EP) with those using the conventional electrosurgical unit setting (ICC-EP, Erbe).

Methods: This multicenter, retrospective, comparative cohort study included 57 patients who underwent VIO-EP and 91 who underwent ICC-EP.

View Article and Find Full Text PDF

Background: Endoscopic ultrasound-guided tissue acquisition is vital for diagnosing pancreatic and peridigestive tract lesions. A new three-prong asymmetry tip needle has been developed for this procedure. In this study, we retrospectively assessed the diagnostic ability, tissue collection volume, and procedural adverse events of the three-prong asymmetry tip needle for solid pancreatic, subepithelial, and other organ lesions.

View Article and Find Full Text PDF

Bile aspiration during endoscopic ultrasound-guided hepaticogastrostomy reduces the risk of bile leakage. Mukai and colleagues devised a method in which side holes for bile aspiration are created using a biopsy punch in a hard type ultra-tapered bougie dilator. Effective bile aspiration was achieved in all four cases attempted.

View Article and Find Full Text PDF

Introduction: In median arcuate ligament syndrome (MALS), the celiac artery is compressed, causing an arcade to develop in the pancreatic head, leading to ischemic symptoms and aneurysms.

Patient Concerns: The patient was diagnosed with borderline resectable pancreatic cancer (PC) and MALS. Endoscopic biliary drainage with a covered metal stent (CMS) was performed for the obstructive jaundice.

View Article and Find Full Text PDF

Objectives: Endoscopic transpapillary gallbladder drainage (ETGBD) is a highly technical procedure, but few studies have evaluated factors that predict its technical success. Therefore, in this study, we sought to identify predictors of technically successful ETGBD.

Methods: One hundred and eighty-two patients who underwent ETGBD for acute cholecystitis at our hospital were retrospectively investigated.

View Article and Find Full Text PDF
Article Synopsis
  • - Tonozuka and colleagues highlight a new ultra-thin peroral cholangioscope designed for challenging biliary stricture cases, featuring a tip diameter of just 2.3 mm.
  • - This innovative cholangioscope simplifies the insertion process compared to conventional scopes, easing accessibility for medical professionals.
  • - It's also cost-effective and versatile, making it a valuable tool in the field of biliary procedures.
View Article and Find Full Text PDF

Transpapillary endoscopic biliary drainage is the gold standard for resolving malignant biliary obstruction. Stent migration occasionally occurs and is troublesome to retrieve. Yamamoto and colleagues report with accompanying video on the successful retrieval of a proximally migrated stent using biopsy forceps through a guiding sheath cannula.

View Article and Find Full Text PDF

Background And Aims: Bilioenteric anastomotic stricture (BES) is a well-known adverse event after bilioenterostomy. Recently, EUS-guided antegrade intervention (EUS-AI) has been developed for cases that are difficult to treat by balloon enteroscopy-assisted ERCP. However, no data are available on the long-term outcomes after EUS-AI.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates how different needle types and the angle of the echoendoscope affect the ease (puncturability) of inserting needles for diagnosing gastrointestinal lesions using EUS-guided techniques.
  • Researchers compared several 22-gauge fine-needle aspiration (FNA) and biopsy (FNB) needles to measure their resistance when being advanced through tissue.
  • Results showed that FNB needles had higher resistance compared to FNA needles, with SharkCore exhibiting the lowest resistance, making it the best option when a tight angle is needed during insertion.
View Article and Find Full Text PDF

This paper discusses a novel tube placement technique; the "spinning lasso method", in EUS-guided drainage for small pancreatic pseudocysts (PC) with video. In general, the placement of a drainage tube can be difficult in a small PC and the tube often deviates during attempted insertions into the cavity. The technique helps to mitigate this problem.

View Article and Find Full Text PDF

Background/purpose: A peroral cholangioscope (POCS) can allow direct visualization of the biliary mucosa and its use is becoming more widespread due to improvements in functionality, image quality, and operability, as well as the development of related devices. Recently, a novel mother-baby peroral cholangioscope (nMB-POCS) with a large (2-mm) accessory channel has been developed. In this study, we evaluated the feasibility of this novel POCS in a dry simulation and animal model.

View Article and Find Full Text PDF

Highlight Interventional endoscopic ultrasound has become widely used although it remains challenging. Nagai and colleagues present the first case of single-session endoscopic ultrasound-guided hepaticogastrostomy and endoscopic ultrasound-guided pancreatic duct drainage, and demonstrate that it is feasible for the management of biliary and pancreatic duct stones in patients with surgically altered anatomy.

View Article and Find Full Text PDF

Background And Objectives: Several studies have demonstrated that EUS-guided fine-needle biopsy (EUS-FNB) is useful for diagnosing gastrointestinal subepithelial lesions (GI SELs). However, there is limited evidence regarding the use of Franseen needles during EUS-FNB for patients with GI SELs. In addition, the optimal approach for diagnosing small SELs is unclear.

View Article and Find Full Text PDF

High-intensity focused ultrasound (HIFU) is a novel advanced therapy for unresectable pancreatic cancer (PC). HIFU therapy with chemotherapy is being promoted as a novel method to control local advancement by tumor ablation. We evaluated the therapeutic effects of HIFU therapy in locally advanced and metastatic PC.

View Article and Find Full Text PDF

We herein report two cases of hemorrhagic ampullary lesions in which endoscopic papillotomy was performed to control bleeding and resulted in successful treatment. Both patients were pathologically diagnosed with an underlying pathology characterized by inflammatory cell infiltration and capillary proliferation. They also had disposing factors for bleeding, such as antithrombotic therapy and idiopathic thrombocytopenic purpura.

View Article and Find Full Text PDF

Background/purpose: Various tumors of the minor duodenal papilla have been reported, most of which are treated by laparotomy. Although early-stage tumors of the major papilla are increasingly being treated by endoscopic resection with relative ease and low invasiveness, there are only a few reports on endoscopic resection of tumors in the minor papilla.

Methods: Six patients with tumors in the minor papilla were treated by endoscopic papillectomy (EP), and their clinical and histopathological data were analyzed retrospectively.

View Article and Find Full Text PDF

Background And Aims: The optimal electrosurgical unit (ESU) settings for endoscopic papillectomy (EP) have not been investigated. We conducted animal experiments to determine the optimal endoCUT settings with VIO (Erbe, Tübingen, Germany) ESUs and then conducted a small clinical study.

Methods: Dedicated animal experimental models were created.

View Article and Find Full Text PDF

Highlight Tsuchiya and colleagues developed a scope holder to maintain good scope positioning during interventional endoscopic ultrasound. The scope holder not only reduces the burden on the endoscopist but also reduces the radiation exposure of the caregiver. This is the first report on a scope holder for flexible endoscopes.

View Article and Find Full Text PDF

Background And Objectives: EUS-guided biliary drainage (EUS-BD) has recently been used for the treatment of not only malignant pancreaticobiliary diseases, but also for benign diseases. In most previous studies, EUS-BD was performed using a fully covered self-expandable metallic stent (SEMS), and data focusing on the usability of plastic stents for benign diseases are limited. We previously developed a plastic stent dedicated to EUS-guided hepaticoenterostomy (EUS-HES), and achieved favorable results in a feasibility study, although most of the patients had malignant diseases.

View Article and Find Full Text PDF

Pancreatic duct stenting is a well-established method for reducing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. However, there is no consensus on the optimal type of plastic stent. This study aimed to evaluate the feasibility and safety of a new 4-Fr plastic stent for pancreatic duct stenting.

View Article and Find Full Text PDF

Background/purpose: We developed EUS-guided double-balloon occluded gastrojejunostomy (EPASS) for gastric drainage tract obstruction. The success of EPASS depends on the proximity of the stomach and the gastrointestinal (GI) tract near the ligament of Treitz. The aim of this study is to clarify the GI anatomy near the ligament of Treitz.

View Article and Find Full Text PDF