Publications by authors named "Kazumasa Hara"
Article Synopsis
- * The research involved 328 patients and used a method called propensity score matching to analyze outcomes, finding higher pain ratings and more rescue medication use in the acetaminophen group compared to the loxoprofen group.
- * Overall, acetaminophen was linked to better renal safety, showing a lower increase in serum creatinine and no cases of acute kidney injury, while loxoprofen showed a 4.9% incidence of acute kidney injury.
Article Synopsis
- The study aimed to assess the effectiveness and safety of using two new drugs, abiraterone and enzalutamide, in sequence after patients received docetaxel therapy for castration-resistant prostate cancer.
- Out of 21 patients, only 11% in the abiraterone group and 9% in the enzalutamide group showed a significant reduction in PSA levels, indicating low effectiveness of the sequential treatment.
- The overall survival rates were similar for both drug groups, and some patients experienced adverse effects that necessitated a change in medication, but the study concluded that combining these therapies provided limited clinical benefits.
Purpose: To evaluate long-term continuous administration of docetaxel (DOC), over survival rate, PSA level and adverse effects were analyzed, retrospectively. We also compared the results of long-term treatment group and short-term treatment group.
Material And Methods: This study reported that 14 cases of long-term continuous administration of DOC consisting of 11 or more cycles among 51 patients of castration-resistant prostate cancer (CRPC) treated with DOC from October 2008 to September 2013 at our institution, retrospectively.