Publications by authors named "Kazuma Ueda"
The mechanism underlying the improvement in hepatic function by liver hydrolysate (LH) after ethanol-induced hepatic injury is unclear. Therefore, we investigated the effects of LH administration on chronic ethanol-induced hepatic injury in normal rats and the mechanism underlying the improvement of its symptoms by LH. LH attenuated liver damage and reduced oxidative stress after chronic ethanol-induced hepatic injury in normal rats.
View Article and Find Full Text PDFRat-derived feeder cells immortalized by expression of mutant CDK4, cyclin D, and telomerase can support stem cell growth.
Biochim Biophys Acta Mol Cell Res
May 2019
Article Synopsis
- Stem cells often need feeder cells for maintenance, with primary mouse embryonic fibroblasts (MEFs) being the traditional choice, but they require frequent isolation since they don't expand indefinitely.
- Immortalized cells like STO have been used as alternatives, but they typically only support stem cell cultures for around 4 to 7 days.
- This study introduces a new type of rat-derived fibroblast that can be immortalized and supports stem cell cultures for about 14 days, offering a more effective and longer-lasting source for feeder cells in stem cell research.
We studied the effects of fermented barley extract P (FBEP) in stroke-prone spontaneously hypertensive rats (SHRSP). Male 10-week-old SHRSP were divided into three groups that were fed: an AIN-93M diet (control), a low dose of FBEP (4 g/kg; FBEP1), and a high dose of FBEP (20 g/kg; FBEP2) for three weeks. Hypertension was significantly improved by the use of FBEP supplementation.
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