Publications by authors named "Kazuki Kawajiri"
Article Synopsis
- - This study assessed how accurately SARS-CoV-2 RNA can be detected in saliva samples, comparing those treated with guanidine and without, against traditional nasopharyngeal swabs (NPS) used as a reference.
- - Results showed that raw saliva had a 100% sensitivity for detecting the virus, while the sensitivity for saliva treated with guanidine-based and guanidine-free inactivators was lower, at 65.9% and 82.9% respectively.
- - Despite the reduced sensitivity in treated saliva, the study found that these inactivated samples could still provide reliable results for diagnosing COVID-19, which is beneficial for minimizing the risk of virus transmission.
High-flow nasal cannula (HFNC) can be effective in treating type 1 respiratory failure by reducing the severity of coronavirus disease 2019 (COVID-19). The purpose of this study was to assess the reduction of disease severity and safety of HFNC treatment in patients with severe COVID-19. We retrospectively observed 513 consecutive patients with COVID-19 admitted to our hospital from January 2020 to January 2021.
View Article and Find Full Text PDFBackground: The current gold standard in coronavirus disease (COVID-19) diagnostics is the real-time reverse transcription-polymerase chain reaction (RT-PCR) assay for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in nasopharyngeal swab (NPS) samples. Alternatively, nasal swab (NS) or saliva swab (SS) specimens are used, although available data on test accuracy are limited. We examined the diagnostic accuracy of NPS/NS/SS samples for this purpose.
View Article and Find Full Text PDF