Publications by authors named "Kazuki Katayama"
Article Synopsis
- Eosinophil inflammation in severe asthma often persists despite high-dose corticosteroid treatment, leading to the development of biologics targeting type 2 cytokines for corticosteroid-resistant cases.* -
- This study investigated the direct effects of type 2 cytokines (IL-4, IL-5, IL-13, TSLP) on eosinophils from healthy individuals, measuring indicators like adhesiveness and superoxide production.* -
- Results indicated that IL-5 significantly enhanced eosinophil functions, whereas IL-4, IL-13, and TSLP did not show such direct effects at clinical concentrations, implying limited eosinophil involvement in the action of certain biologics.*
Background: The standard treatment for patients in good general condition with limited-disease small cell lung cancer (LD-SCLC) is concurrent platinum/etoposide chemotherapy and thoracic radiotherapy (TRT). However, the efficacy and safety of chemoradiotherapy (CRT) in older patients with LD-SCLC has not been fully explored; moreover, the optimal treatment for this patient group remains unclear. This study aimed to investigate the feasibility and efficacy of CRT in older patients with LD-SCLC.
View Article and Find Full Text PDFAnorexia nervosa causes various complications accompanying weight loss and malnutrition. Although bilateral spontaneous pneumothorax (SBSP) is uncommon, caution is needed in anorexia nervosa because this complication can be fatal. We encountered a 17-year-old girl with SBSP from emphysematous pulmonary changes due to anorexia nervosa.
View Article and Find Full Text PDFBackground: In the context of the coronavirus disease 2019 (COVID-19) pandemic, a rapid and reliable point-of-care test is an essential tool for controlling the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In particular, an immunochromatography test (ICT) that uses saliva specimens for rapid antigen detection not only reduces the risk of secondary infections but also reduces the burden on medical personnel.
Methods: The newly developed salivary antigen test kit "Inspecter Kowa® SARS-CoV-2" is an ICT to which saliva specimens can be directly applied.
Background: The prevalence of asthma in elderly population has been increasing. Previous studies have demonstrated clinical characteristics of elderly asthmatics (EA). However, little is known regarding the influence of immunological change on the physiological status of EA.
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