Publications by authors named "Kazuhisa Hongo"
Impaired neuroanatomic development in infants with congenital heart disease.
J Thorac Cardiovasc Surg
January 2009
Objectives: We performed a regional volumetric study of the brain using 3-dimensional magnetic resonance imaging in infants with congenital heart disease to search for variables in anatomic development of the brain that may be associated with functional impairment.
Methods: Forty infants with congenital heart disease-17 infants with single ventricle physiology, 5 with transposition of great arteries, and 18 with ventricular septal defect-were studied prospectively by 3-dimensional magnetic resonance imaging of the brain several months after heart surgery.
Results: The global volume of gray matter was significantly reduced in the patients with congenital heart disease compared with normal controls (P < .
Background: Patients with the mitochondrial (mt) DNA T8993G mutation reportedly have variable neurologic manifestations. In these patients, retinal dystrophies progress from salt-and-pepper appearance to severe diffuse pigmentary retinopathy.
Case: A Japanese boy harboring the mtDNA T8993G mutation had hypotonia, ataxia, and developmental delay.