Publications by authors named "Kazuhiro Uenaka"
Background: Articular cartilage has a limited capacity for spontaneous repair, and its repair remains a clinical challenge. The purpose of this study was to prepare scaffold-free cartilage-like constructs and evaluate the feasibility of their use for the treatment of cartilage and osteocartilage defects in vivo.
Methods: The scaffold-free constructs were prepared by chondrocytes isolated from the articular cartilage of rabbits using a high-density three-dimensional culture system.
Article Synopsis
- The study aimed to assess the impact of adding a CIDR device to the Ovsynch protocol on hormone levels and conception rates in dairy cows with cystic ovarian diseases.
- Dairy cows were classified with cystic ovarian diseases based on the presence of cystic follicles and treated using either the standard Ovsynch protocol or the Ovsynch+CIDR protocol.
- Results showed no significant difference in hormone levels or conception rates between the two treatment groups, but lower estradiol levels on Day 9 were linked to reduced progesterone and lower pregnancy chances.
Background: A scaffold-free cartilage construct, analogous to those found during embryonic precartilage condensation, has received much attention as a novel modality for tissue-engineered cartilage. In the present study, we developed an uncomplicated culture system by which scaffold-free cartilage-like tissues are produced using cell-cell interactions. With this system, we attempted to prevent dedifferentiation and reverse the phenotypic modulations by adjusting the cell density.
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