Publications by authors named "Kazuhiro Torii"
Dermal fibroproliferative disorders impair patients' quality of life. Although several therapeutic approaches exist for treatment of dermal scars, the development of effective ointments with few adverse effects could improve these therapeutic methods. Short-chain and ω-3 polyunsaturated fatty acids are reported to be immunomodulators with anti-inflammatory properties.
View Article and Find Full Text PDFBackground:: A single, effective therapeutic regimen for keloids has not been established yet, and the development of novel therapeutic approaches is expected. Butyrate, a short-chain fatty acid, and docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid, play multiple anti-inflammatory and anticancer roles via their respective mechanisms of action.
Objective:: In this study, we evaluated the antifibrogenic effects of their single and combined use on keloid fibroblasts.
The patient was a 68-year-old woman who had experienced recurrent febrile episodes since 66 years of age. Despite various examinations and treatments, the etiology remained unclear. Further examinations following another referral failed to uncover the cause.
View Article and Find Full Text PDFArticle Synopsis
- Ultrasound therapy is being explored as a potential treatment to enhance healing of pressure ulcers, but its effectiveness and scientific justification remain uncertain.
- The study focused on how ultrasound affects two key proteins, alpha-smooth muscle actin (α-SMA) and transforming growth factor-beta1 (TGF-β1), that are crucial for speeding up wound healing in human skin cells.
- Results showed that ultrasound irradiation increased the expression of both α-SMA and TGF-β1 at 24 hours after treatment, suggesting that ultrasound could play a positive role in chronic wound healing.