Publications by authors named "Kazuhiro Okada"

Background: Traumatic cerebral aneurysms (TA) are a subset of traumatic cerebrovascular injury (TCVI). Misdiagnosis of TA can be fatal. To investigate factors that predict TA formation and the optimal timing for searching, we present four suspected cases of delayed TA rupture during hospitalization.

View Article and Find Full Text PDF

A 24-year-old Japanese female with anorexia nervosa presented to our hospital for bilateral pneumothorax, and 12-Fr thoracostomy catheters were inserted into the bilateral pleural cavities. On hospital day 9, a thoracoscopic bullectomy was performed. However, air leakage relapsed on both sides on postoperative day 1.

View Article and Find Full Text PDF

Background: Persistent inflammation, immunosuppression, and catabolism syndrome (PICS) has impacted on long-term prognosis of patients with trauma. We aimed to identify patients with trauma at risk of PICS-related complications early in the intensive care unit (ICU) course.

Methods: A single-center retrospective cohort study was conducted.

View Article and Find Full Text PDF

Background: Hemiparesis associated with spontaneous spinal epidural hematoma (SSEH) usually occurs ipsilateral to the hematoma. We here report the case of a patient with paradoxical hemiparesis contralateral to a spinal lesion due to SSEH.

Case Presentation: A 70-year-old woman was identified in routine clinical practice; she presented with acute-onset neck pain and left hemiparesis.

View Article and Find Full Text PDF

Background: Among the types of lung resection procedures, pneumonectomy carries the highest risk for mortality. In recent years, bronchovascular double-sleeve lobectomy has been performed for centrally located non-small cell lung cancer involving both the bronchus and the pulmonary artery (PA) in order to avoid pneumonectomy. The use of an autologous pulmonary vein (PV) conduit for PA reconstruction during lung-sparing resections had first been reported in 2009.

View Article and Find Full Text PDF

Typical pulmonary carcinoid (TC) tumors are low-grade neuroendocrine tumors and usually detected as indolent solitary tumors. We herein report a case of multiple pulmonary carcinoid tumors and tumorlets localized in the right lower lobe with no underlying lung disorders suggesting diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). A 28-year-old man with multiple 1-to-8-mm pulmonary nodules in the peripheral pulmonary parenchyma of the right lower lobe was referred to our hospital.

View Article and Find Full Text PDF

Background: The 'golden hour' is a well-known concept, suggesting that shortening time from injury to definitive care is critically important for better outcome of trauma patients. However, there was no established evidence to support it. We aimed to validate the association between time to definitive care and mortality in hemodynamically unstable patients for the current trauma care settings.

View Article and Find Full Text PDF

Background: MicroRNAs (miRNA) are expected as useful biomarkers for various diseases. We studied the pre-analytical factors causing variation in the analysis of miRNA.

Material And Methods: Blood samples were collected from 25 healthy subjects.

View Article and Find Full Text PDF

MicroRNAs (miRNA) are non-coding small RNAs. Exosomes carry extracellular miRNAs in plasma and other body fluids. Levels of plasma miRNAs show disease-specific changes.

View Article and Find Full Text PDF

 It is important to examine the pharynx during upper gastrointestinal endoscopy. Pharyngeal anesthesia using topical lidocaine is generally used as pretreatment. In Japan, lidocaine viscous solution is the anesthetic of choice, but lidocaine spray is applied when the former is considered insufficient.

View Article and Find Full Text PDF

Objective: To describe blood management and anticoagulation practice for cardiac and respiratory extracorporeal membrane oxygenation (ECMO) with consideration of major surgery at the time of its initiation.

Design: A single-center retrospective review over 18 months of blood product usage and anticoagulation in patients treated with veno-venous (VV) ECMO versus veno-arterial (VA) ECMO and after major surgery (Sx) versus no surgery (Nsx).

Setting: Tertiary metropolitan hospital and state ECMO referral and heart and lung transplantation center.

View Article and Find Full Text PDF
Article Synopsis
  • The study explored the benefits of conducting urgent resuscitative surgery (URS) in the emergency department to quickly control bleeding in patients with severe torso trauma and unstable vital signs.
  • A total of 264 cases were analyzed, with patients divided into URS and non-URS groups to compare their survival rates against what was predicted using the Trauma and Injury Severity Score (TRISS).
  • Results showed that patients in the URS group had a higher observed survival rate than predicted, especially those with low blood pressure and moderate coma scores, indicating that URS may significantly improve survival outcomes for critical trauma cases.
View Article and Find Full Text PDF

A 43-year-old woman who had received anticoagulant therapy for atrial fibrillation for 2 years was admitted to our hospital with hematemesis. Endoscopy revealed a huge submucosal hematoma in the antrum of the stomach. Repeat endoscopy on day 6 showed that the submucosal hematoma had developed into a giant ulcer.

View Article and Find Full Text PDF

Aim: To identify patients who can obtain the full benefit from targeted temperature management (TTM) after out-of-hospital cardiac arrest.

Methods: We performed a retrospective observational study of comatose patients treated with TTM after an out-of-hospital cardiac arrest from January 2006 to February 2011. Neurological outcome was evaluated with the Glasgow-Pittsburgh Cerebral Performance category (CPC) at discharge and predictors were determined.

View Article and Find Full Text PDF

N-Carbonylation of less nucleophilic nitrogen compounds was achieved by the reaction of the lithium azaenolates with carbon monoxide and selenium. This reaction proceeds in the cases of amides, formamides, ureas, and carbamates, leading to the formation of the corresponding carbamoselenoates in good to high yields after trapping with BuI.

View Article and Find Full Text PDF

Objective: The goal of this study was to develop an improved (62)Zn/(62)Cu generator based on cation exchange resin and remote preparation at high radioactivity scale for clinical use.

Methods: A natural Cu target was irradiated with proton beam in the energy range of 30-->19 MeV at a beam current of 10 muA for 1 h to obtain around 1.7 GBq of (62)Zn.

View Article and Find Full Text PDF

Mean cerebral blood flow (mCBF) in the slice including the basal ganglia (reference slice) is necessary for the quantification of regional CBF using Patlak plot and BUR methods on 99mTc-ECD cerebral perfusion SPECT. The mCBF was calculated from the mean counts of this slice. A region of interest (ROI) has been manually set on the reference slice to obtain the mean counts (manual ROI method).

View Article and Find Full Text PDF