Publications by authors named "Kazuhiko Sadamoto"

Article Synopsis
  • A study analyzed the prevalence of incidental unruptured intracranial aneurysms (UIAs) in 1,376 healthy older adults (ages 31-91) using MRI and found UIAs in 5.7% of participants, predominantly in women and the anterior circulation.
  • Results indicated that individuals with UIAs were generally older, had more severe hypertension, and exhibited a significantly lower carotid flow pulsatility index compared to those without UIAs.
  • The research suggested a potential link between lower carotid flow pulsatility index and higher low-density lipoprotein cholesterol levels, indicating that these factors might influence the development of UIAs and could inform future aneurysm screening practices.
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Article Synopsis
  • A study analyzed the safety and effectiveness of unilateral focused ultrasound (FUS) thalamotomy to treat essential tremor in 35 Japanese patients, showing positive results over a year-long follow-up.
  • Patients experienced a significant 56.4% reduction in tremor severity and a 46.3% improvement in quality of life, with the reduction in tremors maintained throughout the year.
  • The procedure had a good safety profile with no severe adverse events; the most common issue was temporary gait disturbance that resolved, confirming FUS thalamotomy's effectiveness aligns with previous studies.
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Purpose: Although time-of-flight (TOF)-magnetic resonance angiography (MRA) can clearly depict intracranial arteries, the arterial flow of middle cerebral artery (MCA) is occasionally not detected. We evaluated this phenomenon with reference to cerebrovascular dynamics.

Materials And Methods: Seventeen patients with suspected occlusion of MCA or internal carotid artery on TOF-MRA were enrolled.

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Background: We evaluated the utility of 3-dimensional (3-D) ultrasound imaging for assessment of carotid artery stenosis, as compared with similar assessment via magnetic resonance angiography (MRA).

Methods: Subjects comprised 58 patients with carotid stenosis who underwent both 3-D ultrasound imaging and MRA. We studied whether abnormal findings detected by ultrasound imaging could be diagnosed using MRA.

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Background: Given the very poor outcome of ruptured intracranial aneurysms, detection and treatment of unruptured intracranial aneurysms by a less invasive examination have become important. For this purpose, 3-tesla (3T) magnetic resonance imaging (MRI) is the most suitable candidate, owing to its high signal/noise ratio and frequency resolution. However, few reports have investigated the prevalence of intracranial aneurysms with high-tesla MRI.

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Background: Cerebral microbleed (CMB), which is conspicuous on gradient-echo T2-weighted magnetic resonance imaging, is a risk factor of intracerebral hemorrhage (ICH). CMBs have been detected even in neurologically healthy persons, who also seem prone to be affected by stroke, not only ICH but also cerebral infarction.

Methods And Results: The presence of CMB was investigated in brain dock participants, making reference to silent lacunar infarction (SLI).

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Background And Purpose: We compared 3-dimensional time-of-flight magnetic resonance angiography (3D TOF MRA) using a 3-tesla (T) MR unit with 64-channel multi-detector row computed tomographic angiography (64-MDCTA) for detection and characterization of angiographically proven unruptured intracranial aneurysms.

Methods: Thirty-eight patients with 47 aneurysms and 8 patients without aneurysms underwent 3T, 3D TOF MRA; 64-MDCTA; and intra-arterial angiography. As a first study, 3 radiologists blinded to pertinent clinical information independently reviewed MRA and CTA images.

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Purpose: To evaluate the performance advantages of an 8-element phased array head coil (8 ch coil) over a conventional quadrature-type birdcage head coil (QD coil) with regard to the signal-to-noise ratio (SNR) and image uniformity in 3 Tesla magnetic resonance (MR) imaging.

Materials And Methods: We scanned a phantom filled with silicon oil using an 8 ch coil and a QD coil in a 3T MR imaging system and compared the SNR and image uniformity obtained from T(1)-weighted spin echo (SE) images and T(2)-weighted fast SE images between the 2 coils. We also visually evaluated images from 4 healthy volunteers.

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Dynamic MR imaging provides hemodynamic information about normal and pathologic tissue of the brain. The purpose of our study was to evaluate the usefulness of dynamic MR imaging in the assessment of tumor vascularity and the tumor tissue blood flow of meningiomas. We studied 13 patients with meningiomas using dynamic spin-echo MR imaging.

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