Publications by authors named "Kazuaki Morishita"

Introduction: This study aimed to investigate the clinical and radiological outcome of "indirect decompression" using lateral-posterior combined surgery for osteoporotic vertebral fracture (OVF) with neurological symptoms.

Methods: A total of 17 patients who underwent lateral and posterior combined indirect decompressive spinal reconstruction (LP-IDR) for single-level OVF with neurological symptoms were included in this study. The neurological symptoms (sensory disturbance and muscle weakness) and imaging findings (local angle and height of the fracture segment and bone fragment occupancy in the spinal canal) were investigated preoperatively, postoperatively, and at the 1-year follow-up.

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  • - Traumatic spinal cord injury leads to immediate tissue damage and ongoing secondary injuries that currently lack effective treatment options, requiring new therapeutic strategies.
  • - The study explores the effects of Brilliant Blue FCF, a food-safe dye that inhibits the P2X purinoceptor 7/pannexin1 complex, on spinal cord injury in rats, showing it can reduce damage and enhance motor recovery.
  • - Compared to other compounds like Brilliant Blue G and carbenoxolone, Brilliant Blue FCF effectively lowers inflammation and promotes healing in spinal cord tissues, with similar protective benefits demonstrated across the treatments.
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  • Spinopelvic sagittal alignment is important for understanding balance and treatment results in adult spinal deformity (ASD), and this study specifically examines changes in spinopelvic parameters linked to lumbosacral transitional vertebrae (LSTV).
  • The research involved 371 participants, categorizing them into LSTV+ (with specific types of LSTV) and LSTV- groups, analyzing their spinopelvic parameters, clinical symptoms, and quality of life (QOL).
  • Findings revealed that the LSTV+ group had greater pelvic incidence and differences in specific clinical symptoms and QOL metrics compared to the LSTV- group, highlighting a significant correlation between LSTV and spinal
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Purpose: To determine the most valid bone health parameter to predict mechanical complications (MCs) following surgery for adult spinal deformity (ASD).

Methods: This multicenter study retrospectively examined the records of patients who had undergone fusion of three or more motion segments, including the pelvis, with a minimum two-year follow-up period. Patients with moderate and severe global alignment and proportion scores were included in the study and divided into two groups: those who developed MCs and those who did not.

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Study Design: Retrospective cohort study.

Objectives: The criteria for determining completion of intervertebral stability after posterior lumbar interbody fusion (PLIF) remain controversial. Several new radiological indicators of bone growth and osteointegration have been established.

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  • A study investigated the impact of a new tapered porous titanium cage (3DTi) versus a square PEEK cage (sPEEK) on vertebral endplate injuries during extreme lateral interbody fusion (XLIF) surgeries.* -
  • The study involved 32 patients with lumbar degenerative diseases, comparing preoperative and postoperative spinal alignment and measuring endplate concavity through CT imaging.* -
  • Results showed that the 3DTi cage significantly reduced endplate injuries (8.0%) compared to the sPEEK cage (45%), indicating that the new cage design effectively lessens endplate load during insertion.*
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Study Design: It is a retrospective cohort study.

Objectives: To compare the radiographic and clinical outcomes of serial body casting for infantile idiopathic scoliosis (IIS) with versus without the use of general anesthesia (GA). Serial body casting for IIS has traditionally been performed under GA.

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Background: Several authors mentioned surgical outcome for scoliosis associated with neurofibromatosis type 1 (NF-1). However, no studies have summarized long-term surgical outcomes after surgical treatment of early-onset scoliosis (EOS) with NF-1. The purpose of this study is to evaluate the long-term surgical outcome after early definitive spinal fusion for EOS in NF-1 patients.

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Study Design: A retrospective case series.

Objective: This study aimed to report the sagittal outcome measures in patients with Lenke type 5C adolescent idiopathic scoliosis (AIS) undergoing thoracolumbar/lumbar (TL/L) fusion surgery.

Summary Of Background Data: Previous studies have demonstrated coronal correction of Lenke type 5C AIS by selective TL/L fusion surgery.

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Introduction: The purpose of this study is to demonstrate the clinical characteristics and thoracic factors such as sternal tilt angle and Haller index in patients with idiopathic or syndromic scoliosis associated with pectus excavatum.

Methods: We performed a retrospective review on a cohort of 70 patients (37 males and 33 females) diagnosed with idiopathic and syndromic scoliosis associated with pectus excavatum between 1985 and 2014. We investigated age, location and Cobb angle of the main curve, and thoracic factors including sternal deviation and tilting angle and Haller index using radiographs and computed tomography of the chest.

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Introduction: Gaucher's disease is a congenital metabolic disorder characterized by the accumulation of glucocerebroside in the reticuloendothelial system. Its clinical manifestations include splenomegaly, osteopenia, and pathological fractures. Cases of patients with kyphotic deformities caused by pathological vertebral compression fractures associated with Gaucher's disease are well reported.

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