Publications by authors named "Kazuaki Mizutomi"
Article Synopsis
- The study investigates the histological features associated with Central Fibrous Areas (CFAs) in kidney biopsies, particularly focusing on their relationship with aging and various kidney diseases.
- A total of 101 kidney biopsy samples were analyzed; CFAs were found in 55.4% of these patients, which were made up of various types of collagen.
- Patients with CFAs were generally older and showed higher rates of conditions like hypertension and hyperlipidemia, with specific histological traits being more common in this group compared to those without CFAs.
A 73-year-old Japanese woman was diagnosed with type 1 autoimmune pancreatitis (AIP) without kidney lesions. She was treated with prednisolone (PSL) 30 mg/day, and her AIP symptoms promptly improved, after which the PSL dose was gradually tapered to 5 mg/day. Her renal function had remained normal (serum creatinine 0.
View Article and Find Full Text PDFWe report a case of Henoch- Schönlein purpura nephritis (HSPN) associated with tubulointerstitial nephritis (TIN) and chronic sclerosing sialoadenitis. The patient is a 75-year-old Japanese woman who had bilateral submandibular gland swelling, palpable purpura on the lower legs, and decreased renal function with hematoproteinuria and marked hypocomplementemia, but no skin lesion suggestive of systemic lupus erythematosus (SLE), and did not fulfill the classification criteria for SLE. Her serum IgG4 level was high and immunostaining of renal biopsies revealed marked infiltration by IgG4-positive plasma cells in the interstitium, confirming the diagnosis of IgG4- related disease.
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