In 88 patients with rheumatoid arthritis lipid-protein spectrum of the blood serum were determined biochemically and by means of nefelometric technique, C-reactive protein (CRP) was measured with enzyme immunoassay. An increase in CRP concentration was associated with lowering of apoA1 and HDL FL, triglycerides. Thus, elevation of CRP in RA reflects not only activity of inflammation but also defects in serum lipid-transport system by the atherogenic type.
View Article and Find Full Text PDFBlood rheology was compared in two groups of patients with ischemic heart disease (IHD). In group 1 patients low limbs were amputated. It is in them that rheological properties of blood were changed to the most extent.
View Article and Find Full Text PDFA comparative analysis of major blood lipoprotein values in 108 males aged 16-65 years with lower limbs amputations has shown a higher level of triglycerides (TG) and a reduced level of high density lipoprotein cholesterol (HDL C) in them than in control males with normal limbs. In the subgroup of patients who had undergone the amputation as a result of obliterative arterial disease, the TG level was the highest while HDL C the lowest; moreover, these values appeared to be the same as in the age-matched subgroup of patients with manifestations of atherosclerosis. In the subgroup of older men with posttraumatic lower limb amputations (aged 40-59 years) the TG and HDL C levels did not differ from the corresponding parameters in age-matched subgroup of healthy subjects, whereas young amputees (17-39 years) had the increased blood TG concentration and reduced level of HDL C and apolipoprotein AI.
View Article and Find Full Text PDFEchocardiographic investigation revealed changes in central hemodynamics and myocardial contractility, associated with lasting hypokinesia, in coronary patients after the amputation of a limb that differed significantly from those recorded in patients with intact limbs. Amputation of a limb, lasting hypokinesia, physical overstrain, negative emotions, disorders of myocardial electric and contractile functions, central and peripheral hemodynamic disorders all contribute to the risk of coronary disease, myocardial infarction and death in post-amputation patients.
View Article and Find Full Text PDFIschaemic heart disease (IHD) in patients after amputation of the limbs runs a course with little manifest clinical symptoms, but with high risk of development of myocardial infarction with a lethal outcome. In patients after amputation of limbs there is a decrease of the blood stroke volume, increase of the total peripheral resistance and also marked disorders of the blood rheology and the function of platelets. In patients with IHD after amputation of the limbs for obliterating diseases of the vessels such changes are manifest in disorders of the microrheological properties of the blood (the rate of aggregation of red cell and the stability of red cell aggregates).
View Article and Find Full Text PDFVopr Kurortol Fizioter Lech Fiz Kult
June 1981