[Risk of fetal cytomegaly virus infection depending on number of CMV genome in mother's blood and amniotic fluid].

The cytomegalovirus infection is most common causes of intrauterine infection of the fetus. Using of serologic diagnostic methods the kind of infection is unknown. The aim of the study was assessment of the risk of CMV infection depending of genome account in mother's blood and I amniotic fluid.

[Mediastinal tumor as a cause of fetal hydrops].

Unusual case of fetal hydrops was presented. In a stillborn infant an Rh incompatibility was suspected as a cause of hydrops, although prentally an immunologic source of the illness was excluded. Post-mortem a large polycystic mediastinal teratoma with cardiac and pulmonary hypoplasia was stated as a main cause of the hydrops.

[Diagnostic difficulties of Toxoplasma gondii infection in pregnant women. Is it possible to explain doubts by polymerase chain reaction?].

Objectives: Toxoplasma gondii infection during pregnancy is still a difficult problem in the contemporary perinatology. Difficulties met during interpretation of serological tests carried out in pregnant patients to detect Toxoplasmosis implies more and more frequent use of the Polymerase Chain Reaction (PCR).

Design: To evaluate the dependence between serological tests and quantity of the Toxoplasma gondii genomes in mothers' blood and amniotic fluid or neonatal blood, the quantitative PCR (q-PCR) method was applied.

[Risk assessment for preterm delivery in pregnant women with active periodontitis].

Introduction: Premature labor has been regarded as a highly problematic clinical event not only due to its relation with perinatal mortality but also in the light of the remote results of the prematurity. Therefore many ongoing studies concentrate on evaluation of potentially avoidable risk factors of premature labor. Relatively few studies have suggested chronic periodontitis as such a determinant.

[Value of selected biophysical surveillance methods in prediction and prophylaxis of complications associated with adverse pregnancy outcome in intrauterine growth restriction].

Intrauterine growth restriction is associated with higher rate of complications occurring during pregnancy and in labour, increased morbidity and mortality rate in neonatal period, impaired psychosomatic development in childhood and increased susceptibility for particular diseases in adulthood. For improvement of perinatal outcome it is essential to establish objective criteria based on biophysical surveillance methods for prediction and prophylaxis of adverse outcome in IUGR pregnancies. The aim of the study was to compare selected biophysical surveillance methods in prediction and prophylaxis of complications associated with adverse pregnancy outcome in intrauterine growth restriction.

[Prevention of iron deficiency anemia--influence on the course of pregnancy, delivery and the infant's status].

Iron deficiency is probably the most common nutritional disturbance in the world. At the highest risk, irrespective of economical status, are women at the reproductive age--especially those who are pregnant. Retrospective analysis of a course of gestation, delivery and the infant's status depending on mothers' iron supplementation during pregnancy.

[Changes to the periodontium in postmenopausal women].

Few up to date studies on the influence of hormonal replacement therapy (HRT) on periodontium has been conducted on small groups of patients and the conclusions made may require further investigation on a larger population. It has been widely accepted that decreased estrogen levels in postmenopausal women are associated with a gradual loss of a bone density and increased risk of a dental loss. Much less stress is put however on the fact that the same phenomenon, especially suboptimal levels of estradiol, may deteriorate periodontal tissue condition.

[Frequency of vaginal infections in pregnant women in the Department of Perinatology and Gynaecology in Zabrze].

Objectives: The analysis of vaginal infections in pregnant women admitted to the Department of Perinatology and Gynaecology in Zabrze, from January 2001 to September 2003.

Materials And Methods: They were screened for BV, candidiasis and trichomoniasis. 450 pregnant women (the age of pregnancy 25 +/- 9 weeks gestation) were examined for the presence of these microorganisms in the vagina.

[Etiology of intrauterine growth retardation. Part II: maternal disorders].

The second part of discussion incorporates maternal conditions influencing the risk of intrauterine growth retardation. Special attention was paid to the systemic abnormalities, and those pregnancy related, known for their links with affected placenta-uterine barrier or otherwise related to abnormal fetal growth. Both social and environmental groups of factors potentially influencing prenatal development have been discussed.

[Etiology of intrauterine growth retardation. Part I: placental-fetal interrelationship disorder].

Intrauterine growth retardation (IUGR) increases a risk of perinatal complications and may carry a negative influence on a later baby's mental and physical development. Poorer function revealed by many vital organs seems to be the effect of their lower mass and their relative immaturity. In the first part of a paper the authors discuss two groups of factors thought to be responsible for IUGR.

[Doppler measurements of blood flow velocity and waveforms in fetal venous circulation].

Ultrasonic velocimetry of the fetal circulation became a very useful method in assessment of fetal well-being, especially in high risk pregnancies. There are many papers concerning on distribution and regulation of blood flow in umbilical artery, middle cerebral artery, and much less dealing with flow velocity waveforms in inferior vena cava and ductus venosus and their clinical significance. Fetal compromise is associated with significant alterations in the fetal arterial and venous circulation.

[Antibiotic sensitivity of Enterobacteriaceae isolated from women vagina and uterine cervix].

Unlabelled: Based on performed investigation in the group of 200 women treated for recurrent and chronic vaginitis and cervicitis, the characteristic of isolated microorganism was done. There were found series of drug-resistant bacteria in the vagina and uterine cervical canal in women with recurrent vaginitis and chronic cervicitis. In 42.

[Immunohistochemical localisation of metallothionein in ovarian endometriosis in women].

Objectives: Endometriosis is an illness accompanied by invasion features, but malignant changes appear extremely seldom. Metallothionein (MT) is a protein and takes part in the detoxicating processes of the organism. MT is located, among others, in benign and malignant neoplasms in animals as well as humans, mainly in the S phase of cellular cycle, and that is why MT is considered to be both an index of cell proliferation and tumor progress.

Clinical value of a single serum CA-125 level in women with symptoms of imminent abortion during the first trimester of pregnancy.

Objective: To assess the clinical value of a single serum CA-125 level in women presenting with symptoms of imminent abortion from 5 to 12 weeks' gestation.

Study Design: Two hundred women with symptoms of imminent abortion from 5 to 12 weeks' gestation were allocated to 3 subgroups: group I (n = 50), abdominal pain only; group II (n = 80), abdominal pain and vaginal bleeding of less than 3 days' duration; and group III (n = 70), abdominal pain and vaginal bleeding of > or = 3 days' duration. The control group (n = 55) was women undergoing a normal pregnancy of comparable gestational age.

[Microcytomorphometric video-image detection of nuclear chromatin in ovarian cancer].

Unlabelled: Technology of detection of tissue preparates precisious evaluates contents of nuclear chromatine, largeness and shape of cellular nucleus, indicators of mitosis, DNA index, ploidy, phase-S fraction and other parameters. Methods of detection of picture are: microcytomorphometry video-image (MCMM-VI), flow, double flow and activated by fluorescence. Diagnostic methods of malignant neoplasm of ovary are still nonspecific and not precise, that is a reason of unsatisfied results of treatment.

[Manifestation of glutathione S-transferase GSTM1 and GSTT1 in female patients with bleomycin-positive chromosome instability].

Objectives: The purpose of this research is to assess the incidence of gene polymorphisms coding the GSTM1 and GSTT1 enzymes in a population of female patients with chromosome instability.

Materials And Methods: The PCR method was used to determine the genotype for GSTM1 and GSTT1. The breaks per cell and the percentage of damaged cells were calculated.

[Analysis of mode of delivery in cases with fetal premature atrial contractions].

Objective: Premature atrial contractions are common in obstetrical practise but there is little information available on recommended management and mode of delivery.

Design: The aim of the study was to describe our clinical experience in the management of fetal arrhythmia including the indications for certain time and way of labour.

Materials And Methods: 128 fetuses with diagnosed supraventricular arrhythmia described as atrial extrasystole were examined.

[Serum CA125 variability--new aspects of clinical usefulness].

Serum levels of CA125 turned out to be a valuable parameter not only as a marker of ovarian carcinoma but also in other fields of obstetrics and gynaecology. Up to date most of the studies dealing with the subject remain experimental and their clinical usefulness is not widely acknowledged. Accessible and relatively cheap tests measuring the serum level of this antigen together with its proven clinical value might contribute to a more frequent and much wider use than it takes place contemporarily.

[Serum levels of CA-125 antigen during the first trimester of pregnancy complications and the risk of miscarriage].

Background: The ultrasound, serum beta-HCG and progesterone titres are widely used to assess the risk of miscarriage at the early stages of pregnancy. Though very useful, they are not considered as satisfactorily accurate predictors of imminent abortion during the first three months of pregnancy.

Aim Of Study: Prospective evaluation of clinical usefulness of serum CA125 from 4-12th week of pregnancy in a group of women with symptoms of imminent abortion.

[Rare case of a malignant brain neoplasm in an 18-years old pregnant woman].

Authors presented rare case of anaplastic ependymoma diagnosed in the first trimester of pregnancy 18-years of age patient. Main symptoms of increased intracranial pressure and cerebral edema were vomits, severe headache and apathy. In the sixteen week of pregnancy performed craniotomy and evacuated malignant tumor of region IV ventricle trunk of the brain.

The influence of calyculin A on lymphocytes in vitro.

Human lymphocytes were cultured in vitro and treated with calyculin A. The aim of this work was to estimate the influence of calyculin A on chromosome morphology and banding patterns. It was also interesting whether calyculin A treatment is useful in cytogenetic analysis of human karyotype.

[New methods of monitoring the fetus during labor--detection of intrapartum fetal hypoxia by electrocardiography].

The biophysical diagnostic methods are an essential element of evaluation of the fetus state in pregnancy and delivery. Nowadays, the applied methods of fetus supervision during labour don't ensure the permanent analysis and they don't deliver diagnostic information about fetus hypoxia. With a view to avoiding the risk of fetus injury and its hypoxia technologies should be developed which allow to make a diagnosis of perils to good fetus condition and detection of intralabor hypoxia.

[Level of CA 125 antigen in serum of first trimester normal and miscarried pregnancy].

The ultrasound and titres of serum beta-HCG and progesterone are widely used to assess the risk of miscarriage at early stages of pregnancy. Although very useful, they are not considered as satisfactorily sensitive tests during the first three months of pregnancy. Therefore, their value is limited.

[Ovarian tumors in pregnancy].

Objectives: The presence of adnexal tumours in pregnancy is a significant problem for obstetricians requiring quick diagnosis and operation.

Materials And Methods: The paper presents 22 cases of ovarian tumours diagnosed and treated during pregnancy. In 12 cases laparoscopical cystectomies were performed, in 10 cases laparotomies were done.