Publications by authors named "Kazi Hamid Ali"

Objective: To analyse the correlation of dietary factors with haemoglobin concentration and body mass index.

Methods: This cross-sectional study was conducted in Shaheed Benazirabad district of the Sindh province in Pakistan from September 2015 to April 2016, and comprised students randomly selected from government schools. Data concerning dietary intake, such as meat, milk, egg and fruits, was noted.

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Crocetin, a carotenoid compound, has been shown to reduce expression of inflammation and inhibit the production of reactive oxygen species. In the present study, the effect of crocetin on acute lung injury induced by lipopolysaccharide (LPS) was investigated in vivo. In the mouse model, pretreatment with crocetin at dosages of 50 and 100 mg/kg reduced the LPS-induced lung oedema and histological changes, increased LPS-impaired superoxide dismutase (SOD) activity, and decreased lung myeloperoxidase (MPO) activity.

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Crocetin, a unique carotenoid with potent antioxidative and anti-inflammatory activities, is a major ingredient of saffron used as an important spice and food colorant in various parts of the world. In the present study, the effects of crocetin on platelet activity and thrombosis formation were systematically investigated. Crocetin showed a dose-dependent inhibition of platelet aggregation induced by ADP, collagen, but not by arachidonic acid (AA).

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