Assessing person-centred care: An item response theory approach.

Background And Objectives: Given recent advances in psychometric assessment, there is a need for assessment studies using modern test theory in the field of person-centred care, mainly due to the dominant use of analytical strategies based on classical test theory. The main objective of the present study was thus to examine whether selected items from commonly used instruments of person-centred care were able to differentiate between respondents with a reasonably even level of measurement precision across different regions of the construct range using item response theory (IRT).

Research Design And Methods: A Swedish sample of care staff in elderly care (N = 1342) completed a survey including a selection of items from three previously validated measures of person-centred care.

Long-term effect of bariatric surgery on body composition in patients with morbid obesity: A systematic review and meta-analysis.

We performed a meta-analysis to provide quantitative estimates of fat mass (FM) and fat-free mass (FFM) changes in patients following bariatric surgery over 1 year. A systematic search of PubMed, SCOPUS and Web of Science databases was conducted; the pooled weighted mean difference (WMD) and 95% confidence intervals (CI) were calculated using a random-effects model. Thirty-four studies including Roux en-Y gastric bypass (RYGB), sleeve gastrectomy (SG) biliopancreatic diversion (BPD) and gastric banding (GB) were analyzed.

Self-image and social-image of the donors: Two different views from oocyte donors' eyes.

To identify the perceptions of women oocyte donors this qualitative study was conducted on 30 oocyte donors using in-depth interview. The three main categories of decision-making challenge, the consequences of participation in assisted reproductive treatment, and the contrast between the self-image and social-image of the donor were inferred. Financial and altruistic motivation, social taboo, and the approval of trusted people were the sub-categories of the decision-making challenge.

Effects of a Psychobiotic Supplement on Serum Brain-derived Neurotrophic Factor Levels in Depressive Patients: A Analysis of a Randomized Clinical Trial.

Background/aims: Psychobiotics are probiotics or prebiotics that, upon ingestion in adequate amounts, yield positive influence on mental health via microbiota-gut-brain axis regulation to modulate the circulating cytokines, chemokines, neurotransmitters, or neurotrophins levels. We have recently shown that a psychobiotic combination ( R0052 and R0175; CEREBIOME) significantly improved depression symptoms in patients with depression. Recent animal data suggest the influence of the gut microbiota on brain-derived neurotrophic factor (BDNF), which was shown to correlate with antidepressant response in depressive patients.

Development and Psychometric Analysis of the Measure of Perceived Adherence to the Principles of Medical Ethics in Clinical Educational Settings: Trainee Version (PAMETHIC-CLIN-T).

Objective: This study was conducted to develop and assess psychometric properties of the "Measure of Perceived Adherence to the Principles of Medical Ethics in Clinical Educational Settings: trainee version (PAMETHIC-CLIN-T)" as a data collection tool to enhance research performance rigor in future medical ethics studies.

Patients And Methods: A multi-tiered six stage procedure was applied to develop the PAMETHIC-CLIN-T and assess its psychometric properties in a sample of Iranian medical science undergraduate students (n=263). The final constructed item pool contained 16 questions with the response options in five Likert-type categories.

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited.

Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19.

Design, Setting, And Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin.

Changes in prenatal depression and anxiety levels in low risk pregnancy among Iranian women: A prospective study.

Introduction: Increasing of depression and anxiety in high risk pregnancy is well known but there is limited information on the changes of psychological symptoms in low risk pregnancies and the aim of the study was evaluation depression and anxiety changes in pregnant women with high risk pregnancy.

Methods: This prospective study was performed on 256 pregnant women at the beginning of the first trimester of pregnancy. Inclusion criteria included the absence of pre-pregnancy depression and anxiety and poor pregnancy history.

Influence of dielectric coatings on pin-to-rod nanosecond-pulsed discharges in phosphate-buffered saline.

Plasma medicine is a rapidly expanding field that utilizes non-equilibrium plasma discharges at atmospheric conditions or in liquids for clinical applications. There is significant interest in the production of plasma in the liquid phase for wastewater treatment, agricultural applications, and medical purposes. However, little investigation has been done about the effects of dielectric coatings on submerged electrodes, which is of significant interest to limit electrical current flow in the liquid.

Global public health significances, healthcare perceptions of communities, treatments, prevention and control methods of COVID-19.

Background: The Novel Coronavirus Disease 2019 (COVID-19) has proved to be one of the most burdensome respiratory disease outbreaks ever. Moreover, the public health emergency of the COVID-19 outbreak has been seen by the World Health Organization (WHO) as global health concern since March 2020 and there has been a significantly increased morbidity and mortality in the community worldwide. The objective of this review is to describe and review the global public health significances and community and healthcare perception of features, treatments, prevention and control methods to slow the transmission of the outbreak.

The level of risk, effects response to potential health emergencies, prevention and control method of COVID-19: A systematic review.

Background: COVID-19 is currently the major public health burden in the world, with disease and death in the global community from COVID-19 increasing rapidly from time to time worldwide. However, there has been a lack of well-organized information about the level of risk, effects, prevention and control methods of the disease. Therefore the aim of this study is to identify and review a published level of risk, effects response to potential health emergencies, prevention, and control methods of COVID-19 at a global level.

Impact of motivational interviewing on early childhood caries: A systematic review and meta-analysis.

Background: The authors aimed to assess the scientific evidence on motivational interviewing for the clinical reduction of early childhood caries compared with traditional dental health education.

Methods: Search terms were selected on the basis of Medical Subject Headings and non-Medical Subject Headings terms. The main key words were motivational interviewing, early childhood caries, and education.

Global burden of COVID-19: Situational analyis and review.

Background: The novel Coronavirus Disease 2019 (COVID-19) is the major public health burden in the world. The morbidity and mortality of the global community due to this disease is dramatically increasing from time to time.

Objective: This situational analysis is aimed to analyse prevalence and incidence of COVID-19 and to provide clear information about this disease for the scientific community, stakeholders, healthcare practitioners and decision-makers.

Premarital Screening Program for Congenital Factor XIII Deficiency in Iran.

Background: Factor XIII deficiency is one of the most severe congenital bleeding disorders with high rate of life-threatening bleeding including central nervous system bleeding, umbilical cord bleeding, and recurrent miscarriages. Due to the highest global incidence of the disorder in Iran, this study aimed to design a premarital screening program in Iran.

Methods: This descriptive study was performed on 30 couples with a positive family history of factor XIII deficiency.

Safety and Efficacy of Clobetasol Propionate 0.05% Emollient Foam for the Treatment of Central Centrifugal Cicatricial Alopecia.

Background: There is currently an unmet need for the treatment of women with central centrifugal cicatricial alopecia (CCCA). Objective: To evaluate the safety and efficacy of Clobetasol propionate 0.05% emollient foam for the treatment of women with CCCA.

Analysis of the Iranian maternal mortality surveillance system and providing system improvement strategies: study protocol for strategy formulation.

Background: The implementation of the maternal mortality surveillance system in Iran has significantly reduced the incidence of maternal mortality. However, the pattern of the causes of the mortalities, which has remained constant over the years, are still concerning. This study aimed to explain the experiences of the actors of the Iranian maternal mortality surveillance and provide strategies for improving this system.

Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia.

Objectives: The current study aimed to investigate the relationship of genetic polymorphism and plasma methotrexate (MTX) levels, toxicity experience and event free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL).

Materials And Methods: The study included 74 ALL patients. Polymerase chain reaction and genotyping of methylene tetrahydrofolate reductase (MTHFR) rs1801133, MTHFR rs1801131, ATP-binding cassette superfamily B1 (ABCB1) rs1045642, ATP-binding cassette superfamily G2 (ABCG2) rs2231142 and solute carrier 19A1 (SLC19A1) rs1051266 genetic variations were performed.

Response latencies and eye gaze provide insight on how toddlers gather evidence under uncertainty.

Toddlers exhibit behaviours that suggest judicious responses to states of uncertainty (for example, turning to adults for help), but little is known about the informational basis of these behaviours. Across two experiments, of which experiment 2 was a preregistered replication, 160 toddlers (aged 25 to 32 months) identified a target from two partially occluded similar (for example, elephant versus bear) or dissimilar (for example, elephant versus broccoli) images. Accuracy was lower for the similar trials than for the dissimilar trials.

Neurologic and neuroimaging findings in patients with COVID-19: A retrospective multicenter study.

Objective: To describe neuroimaging findings and to report the epidemiologic and clinical characteristics of patients with coronavirus disease 2019 (COVID-19) with neurologic manifestations.

Methods: In this retrospective multicenter study (11 hospitals), we included 64 patients with confirmed COVID-19 with neurologic manifestations who underwent a brain MRI.

Results: The cohort included 43 men (67%) and 21 women (33%); their median age was 66 (range 20-92) years.

Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial.

This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA ( = 188), PCEM ( = 194), or RCT ( = 168) arms. Preoperative "Pain Intensity" (PI) on Numerical Rating Scale and postoperative PIs until day 7 were recorded.

Oocyte donor's emotions towards the potential offspring: Development and psychometric properties.

Objective: The aim of the present study was to develop a questionnaire for assessing the emotional feelings of the women donors towards the potential offspring resulting from assisted reproductive techniques.

Study Design: Construct validity was evaluated in a cross-sectional study of 150 Iranian oocyte-donating women who undergoing donor egg programs in Isfahan- Iran. The self-report questionnaire was completed within one to ten days after the oocyte donation.

Using social cognitive theory to explain physical activity in Iranian women preparing for pregnancy.

Despite the known useful effects of regular physical activity during the preconception period on pregnancy outcomes, sedentary lifestyle is a prevalent phenomenon in reproductive-aged women. Using social cognitive theory (SCT) as its theoretical framework, the aim of this study was to explain physical activity model in the women preparing for pregnancy in Isfahan, Iran. This cross-sectional study was conducted on 220 Iranian women undergoing preconception care.

Consensus Guidelines of the French Society of Neuroradiology (SFNR) on the use of Gadolinium-Based Contrast agents (GBCAs) and related MRI protocols in Neuroradiology.

Gadolinium-based contrast agents (GBCAs) are used in up to 35% of magnetic resonance imaging (MRI) examinations and are associated with an excellent safety profile. Nevertheless, two main issues have arisen in the last two decades: the risk of nephrogenic systemic fibrosis and the risk of gadolinium deposition and retention. As a first step, this article reviews the different categories of GBCAs available in neuroradiology, their issues, and provides updates regarding the use of these agents in routine daily practice.

Exercise improves neurotrophins in multiple sclerosis independent of disability status.

Background: To date, studies examining the effect of exercise on neurotrophic factors in MS are contradictory, and this may be explained, in part, by moderators such as disability status. To investigating the effect of a 12-week (3sessions/week) supervised multimodal exercise program on neurotrophic factors levels.

Methods: Ninety four women with MS were randomly assigned into exercise or control conditions with randomization stratified by Expanded Disability Status Scale (EDSS) scores of low (EDSS< 4.