Attenuation of potassium dichromate and sodium arsenite toxicities by methanol extract of in mice.

Objectives: Exposure to arsenic and hexavalent chromium is a major public health concern especially in the developing part of the world and there is paucity of information on reliable treatment modalilities. It is in this regard that this study evaluates the efficacy of methanol leaf extract of (MRV) when used as pretreatment agent against potassium dichromate (KCrO) and sodium arsenite (NaAsO) exposure.

Methods: Swiss albino mice between 7 and 10 weeks old were divided into eight cohorts of five animals each.

Potassium Dichromate Toxicities: Protective Effect of Methanol Extract of Corchorus olitorius in Albino Rats.

Exposure to hexavalent chromate compounds such as other human carcinogens is unavoidable in the developing countries of the world. Research efforts are being directed toward minimizing exposure to them, intercepting their activity in vivo, and/or prophylaxis. The present study therefore evaluates the effect of methanol extract of the leafy vegetable, Corchorus olitorius (MECO), against potassium dichromate (K2Cr2O7)-induced toxicities.

Comparative hepatotoxicity and clastogenicity of sodium arsenite and three petroleum products in experimental Swiss Albino Mice: the modulatory effects of Aloe vera gel.

Petroleum products (PPs) consist of complex chemical mixtures, mainly hydrocarbons. Their composition varies considerably with source and use. Inappropriate manual handling and use of PPs, in countries like Nigeria, results in excessive skin contact with the possibility of hazard to health.

Exposure of laboratory mice to domestic cooking gas: implications for toxicity.

The ability of domestic cooking gas to induce hepatotoxicity and clastogenicity in mice was studied. The mice were exposed to domestic gas for twenty-one days at doses of 100 mg/kg, 200 mg/kg and 300 mg/kg respectively. The positive control group of mice were given sodium arsenite intraperitoneously at a dose of 2.