Lifetime Alcohol Use Influences the Association Between Future-Oriented Thought and White Matter Microstructure in Adolescents.

Aims: Future orientation, or the ability to plan ahead and anticipate consequences, is a capacity that develops during adolescence, yet its underlying neurobiology is unknown. Previous independent reports suggest that reduced future orientation and altered white matter microstructure are associated with greater alcohol use in adolescents; however, these effects have not been studied in conjunction. This study investigated the association between future orientation and white matter microstructure as a function of lifetime alcohol use.

SRF selectively controls tip cell invasive behavior in angiogenesis.

Efficient angiogenic sprouting is essential for embryonic, postnatal and tumor development. Serum response factor (SRF) is known to be important for embryonic vascular development. Here, we studied the effect of inducible endothelial-specific deletion of Srf in postnatal and adult mice.

A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes.

Myelin is the multi-layered glial sheath around axons in the vertebrate nervous system. Myelinating glia develop and function in intimate association with neurons and neuron-glial interactions control much of the life history of these cells. However, many of the factors that regulate key aspects of myelin development and maintenance remain unknown.

[Changes in the acid-base status of the synovial fluid in rheumatoid arthritis patients].

Aim: The study of changes in joint fluid (JF) acid-base balance in RA patients to evaluate severity of joint lesions, efficacy of on-going therapy and to predict appearance and persistence of RA remission.

Materials And Methods: A routine examination and measurements of JF pH of the affected joints and venous blood before and during the treatment were performed in 65 RA patients with articular or articular-visceral forms (46 and 19 patients, respectively). 19 patients were seropositive and 20 seronegative by rheumatoid factor.

Studies in developmental cytomechanic.

One of the most promising trends in modern developmental and cell biology, recently defined as <>, or <>, is directed towards revealing the role of mechanical stresses, chemomechanical transduction and active stress responses of cells antissues of developing embryos. We review here the results obtained in this field by our research group and compare them with those from other labs. Our studies relate to the buds of hydroid polypes and to amphibian embryos.

[Ultraweak emissions from chicken eggs and embryos: the nonadditive interaction of 2 emitters and stable nonequilibrium].

Ultraweak emission of the optic range from developing, unfertilized, and dead chicken eggs and their components (isolated blastoderm and embryo, entire yolk, white, and shell) was measured at the normal and abnormal temperatures of incubation using a photomultiplier tube. Two sources of ultraweak emission were found: blastoderm and yolk from the fertilized eggs until day 4 of incubation and shell from all eggs, including the unfertilized and dead ones. Emission from the former source was weaker and almost light independent, was recorded only at the temperature of incubation, and had a wavelength of no more than 3000 nm.

X-ray microanalysis of ion contents in vacuoles and cytoplasm of the growing tips of a hydroid polyp as related to osmotic changes and growth pulsations.

Growth pulsations (GP) in hydroid polyps are associated with changes in vacuolar patterns which can be imitated by altering external osmolarity. With the use of X-ray spectroscopy we measured the elemental contents in the vacuoles and cytoplasm of the growing tips of a hydroid polyp, Podocoryne carnea, under various tonicity conditions. Under hypertonic condition which arrested the samples at the retraction phase of normal GP, the elemental content within the vacuolar compartment appeared to be similar to that of the external medium, confirming our previous conclusion about the dehermetization of the vacuolar compartment under these conditions.

[The calcium content in the bile of patients with cholelithiasis, chronic hepatitis, liver cirrhosis and in healthy subjects].

Measurements of calcium levels in the blood of normal subjects and patients with cholelithiasis, chronic hepatitis, and liver cirrhosis have revealed that biliary calcium levels during the physicochemical stage of cholelithiasis are much higher than during the calculi formation stage and that in chronic hepatitis and liver cirrhosis C bile calcium content is much higher than B bile calcium content.

[Effect of flavin coenzymes on the pyridoxine treatment of avitaminosis B6].

Studies on rats with experimental vitamin B6 deficiency have shown that the combined use of pyridoxine and flavine coenzymes affects the supply of rats with these vitamins. Flavine coenzymes have been found to promote more efficient normalization of pyridoxine and riboflavin balance in the body and to improve the general status of the animals, to increase the excretion of riboflavin and 4-pyridoxic acid with urine, to prove more rapid cure of vitamin deficiency.

[Effect of the combined use of flavin coenzyme preparations and pyridoxine on the body vitamin balance in animals].

The effect of combined administration of flavin coenzymes and pyridoxine on B2-avitaminosis rats' supply with these vitamins has been studied. It has been disclosed that pyridoxine promotes more effective normalization of riboflavin and pyridoxine balance in the body, this balance being measured from the excretion of riboflavin and 4-pyridoxin acid with urine as well as from the content of total flavins in blood and tissues. In vitamin B2 lack, it is recommended that pyridoxin be combined with flavin mononucleotide and in particular with flavin adenine dinucleotide.