[BCG ostitis in children: the epidemiological parameters of some regions of the Russian Federation].

The incidence of BCG ostitis was studied by the data of questionnaires sent from 36 areas of the Russian Federation (RF). Particular emphasis is laid on 15 northwestern RF regions where an indepth study dealing with the 2000-2004 detection rates of postvaccination osseous complications was conducted. The mean incidence rate was 6.

[Immunoenzyme cytochemical methods, monoclonal antibodies and lectins in the diagnosis of tumors of the lymphoid tissue in children].

ICO, IPO and LT series monoclonal antibodies, lectins, PAP and APAAP methods were used to study blood, bone marrow and lymph node cells in children with acute lymphoblastic leukemia (ALL), non-Hodgkin's malignant lymphomas and Hodgkin's disease. The immunological phenotype of malignant lymphoid cells has been characterized and cytological variants of ALL and lymphomas of T and B cell origin have been distinguished.

[Study of lymphocyte subpopulations using peanut, soybean and snail lectins].

The method of penning in plastic dishes was to isolate the PNA+ and PNA- cell populations from the tonsil tissue. Carbohydrate determinants of lymphoid cell surface membranes being at varying stages of antigen-independent and antigen-dependent differentiation have been studied with the use of peanut, soya and edible snail lectins conjugated with horse radish peroxidase.

[Use of monoclonal antibodies and lectins in the study of subpopulations of lymphoid cells in normal state and in leukemia].

The heterogeneity of cell populations with peanut agglutinin receptors in reactive tonsilar tissue has been stated. It contains B lymphocytes (HLA-DR+, CD 10+, IPO-10+ cells), part of T-cells (CD 4+), but no CD 8+ lymphocytes. PNA+ CD 10+ cells are the normal analogues of centrocytic non-Hodgkin's lymphomas.

[Pharmacokinetic research on theophylline].

Blood serum theophylline concentrations were studied in 6 volunteers and 8 patients with bronchospastic syndrome by using an enzyme immunological assay with a commercial kit "Fedesim" (USA) at intravenous and oral administration of euphylline in a dose of 5 mg/kg. The maximal concentration at intravenous injection of euphylline was reached in volunteers in 15 minutes, at oral administration--in 90 minutes, and in patients--somewhat later.