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Publications by authors named "Kayoko Senuma"

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Evidence of different pharmacokinetics including relationship among AUC, peak, and trough levels between cyclosporine and tacrolimus in renal transplant recipients using new pharmacokinetic parameter--why cyclosporine is monitored by C(2) level and tacrolimus by trough level--.
Hironori Takeuchi Naoto Matsuno Kayoko Senuma Toshihiko Hirano Takayoshi Yokoyama

Biol Pharm Bull

January 2008

Article Synopsis
  • - The effectiveness of calcineurin inhibitors in kidney transplant patients is closely linked to how their drug levels are monitored, specifically looking at the area under the concentration-time curve (AUC).
  • - For cyclosporine (CYA), blood levels are typically checked 2 hours after taking the drug, while for tacrolimus (TAC), levels are measured just before the next dose (trough concentration).
  • - This study compared the blood concentration patterns of CYA and TAC in kidney transplant patients with similar backgrounds, revealing notable differences in their pharmacokinetics and how their levels relate to AUC.
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[Survey of the first year of students under the six-year pharmacy curriculum in Tokyo university of pharmacy and life science].
Kayoko Senuma Sakae Unezaki Hironori Takeuchi Masahiro Hayashi

Yakugaku Zasshi

July 2007

The six-year curriculum has been introduced into all pharmacy schools in Japan since April 2006. Those schools are currently preparing for an additional two years of pharmacy education and are in the process of reading the necessary educational infrastructure. However, students' expectations of the new curriculum and understanding of the professional roles of a pharmacist have yet to be investigated.

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Synopsis of recent research by authors named "Kayoko Senuma"

  • - Kayoko Senuma's research primarily focuses on the pharmacokinetics of calcineurin inhibitors, particularly examining the differences in monitoring practices for cyclosporine and tacrolimus in renal transplant recipients, highlighting the relevance of AUC in therapeutic efficacy.
  • - In her 2008 article, Senuma investigates the rationale behind the differing monitoring times for these medications, concluding that the timing of blood sample collection is crucial for optimizing patient outcomes in transplant settings.
  • - Additionally, Senuma has contributed to understanding pharmacy education through her 2007 survey on students' perceptions of the new six-year pharmacy curriculum implemented in Japan, emphasizing the need to assess student expectations and professional role comprehension.

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