Publications by authors named "Kayoko Fukui"
Background: Behavioural and psychological symptoms of dementia (BPSD) negatively impact the quality of life of patients with dementia and their surrounding caregivers. Therefore, identifying modifiable factors to prevent BPSD is crucial. This cross-sectional study investigated the association between hearing impairment (HI), social relationships, and BPSD.
View Article and Find Full Text PDFOne of the goals of oral healthcare management is to manage dry mouth. Thus, moisturizers containing antimicrobial ingredients, such as hinokitiol (HT), are applied to the oral mucosa after oral care. In this study, we investigated the preventive effect of HT against the growth of Candida albicans (C.
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- Oral mucositis is common in the elderly, making oral care challenging, and conditions like candidiasis can lead to serious systemic infections.
- A study aimed to compare the effectiveness of antifungal prophylaxis versus oral care in preventing systemic fungemia using a mice model, where different groups received either oral care or antifungal treatments.
- Results showed that groups receiving antifungal treatment had lower fungal counts and fewer instances of systemic infection compared to the oral care group, suggesting antifungal prophylaxis may be a viable option for preventing serious infections in those with poor oral care.
Article Synopsis
- Amitriptyline, a tricyclic antidepressant used for chronic orofacial pain, may alter oral microflora and innate immunity, though its specific effects were previously unclear.
- In a study with Sprague-Dawley rats, amitriptyline was administered for two weeks, during which researchers analyzed changes in the oral microbiome and antimicrobial peptide levels through DNA sequencing and mRNA evaluation.
- Results revealed significant shifts in oral bacteria composition and increased antimicrobial peptide expression in the amitriptyline group, indicating that this medication may influence oral health and immunity.
Measuring the production of Candida dubliniensis (C. dubliniensis) phospholipase B (PLase B) by the Price's method has long been considered to be unattainable because the levels of PLase produced are undetectable. In this study, C.
View Article and Find Full Text PDFThe causes of fungemia include immunosuppression and neutropenia stemming from diverse factors as well as the placement of central venous catheters. However, the relationship between fungemia and the oral cavity has not been substantiated. In this study, we explored the pathological conditions of Candida albicans-derived oral candidiasis in a mouse model, which always develops oral mucositis as a complication.
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