Publications by authors named "Kayo Yamagiwa"
Article Synopsis
- The Coupling study investigated how vascular biomarkers and supine blood pressure (BP) impact the risk of major cardiovascular events in outpatients over 30 with cardiovascular risk factors, involving 4716 participants during a median follow-up of 5 years.* -
- Key findings revealed that higher cardio-ankle vascular index (CAVI) and lower ankle-brachial index (ABI) are associated with increased cardiovascular event risk, particularly when CAVI is ≥8.0 and ABI is ≤1.10.* -
- The study emphasizes that uncontrolled supine hypertension (≥140/90 mmHg) is a significant risk factor, suggesting a need for better management of BP and vascular health in clinical practice, given that traditional
Background: Inconsistencies between the office and out-of-office blood pressure (BP) values (described as white-coat hypertension or masked hypertension) may be attributable in part to differences in the BP monitoring devices used.
Methods: We studied consistency in the classification of BP control (well-controlled BP vs. uncontrolled BP) among office, home, and ambulatory BPs by using a validated "all-in-one" BP monitoring device.
Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the occurrence of cardiovascular and renal complications in patients with type 2 diabetes mellitus (T2DM) and represent guideline-recommended therapy in this indication. However, precise mechanisms underlying the beneficial cardiovascular effects of SGLT2 inhibitors are not fully understood. This study investigated the effects of the SGLT2 inhibitor, luseogliflozin, on arterial properties and home blood pressure (BP) in patients with T2DM.
View Article and Find Full Text PDFThe value of the cardio-ankle vascular index (CAVI) increases with age. All large-scale studies of the CAVI have investigated patients <80 years old. Thus, the clinical characteristics of high CAVI in patients aged 80 or more remain unclear.
View Article and Find Full Text PDFVascular biomarkers, including the cardio-ankle vascular index (CAVI), are increasingly being recognized as important indicators of cardiovascular risk. CAVI has been shown to have good discriminative ability for detecting new-onset hypertension, but results of studies investigating cardiovascular risk prediction are inconsistent. Furthermore, there is a lack of data on the prognostic value of changes in CAVI over time.
View Article and Find Full Text PDFBackground: Nocturnal blood pressure (BP) is an independent risk factor of cardiovascular events. The NOCTURNE study, a multicenter, randomized controlled trial (RCT) using our recently developed information and communication technology (ICT) nocturnal home BP monitoring (HBPM) device, was performed to compare the nocturnal HBP-lowering effects of differential ARB-based combination therapies in 411 Japanese patients with nocturnal hypertension (HT).
Methods and results: Patients with nocturnal BP ≥120/70 mmHg at baseline even under ARB therapy (100 mg irbesartan daily) were enrolled.
Article Synopsis
- The J-HOP study involved 4,310 Japanese participants, focusing on determining the best timing for home blood pressure measurement to predict stroke and coronary artery disease risk.
- Findings indicated that morning systolic blood pressure (SBP) was a better predictor for stroke than evening SBP or traditional risk factors, improving risk discrimination significantly.
- It was concluded that morning home SBP should be prioritized for stroke risk assessment, though further research is needed across different ethnic groups to validate these findings.
To study whether sleep blood pressure (BP) self-measured at home is associated with organ damage, the authors analyzed the data of 2562 participants in the J-HOP study who self-measured sleep BP using a home BP monitoring (HBPM) device, three times during sleep (2 am, 3 am, 4 am), as well as the home morning and evening BPs. The mean sleep home systolic BPs (SBPs) were all correlated with urinary albumin/creatinine ratio (UACR), left ventricular mass index (LVMI), brachial-ankle pulse wave velocity (baPWV), maximum carotid intima-media thickness, and plasma N-terminal pro-hormone pro-brain-type natriuretic peptide (NTproBNP) (all P<.001).
View Article and Find Full Text PDFBackground: Several guidelines recommend that home blood pressure (HBP) be measured both in the morning and in the evening. However, there have been fewer reports about the clinical significance of morning HBP than about the clinical significance of evening HBP.
Methods: Our study included 4,310 patients recruited for the Japan Morning Surge Home Blood Pressure Study who had one or more cardiovascular risk factors.