Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.

Age-associated B cells (ABCs) are formed under inflammatory conditions and are considered a type of memory B cell (MBC) expressing the transcription factor T-bet. In SLE, ABC frequency is correlated with disease, and they are thought to be the source of autoantibody-secreting cells. However, in inflammatory conditions, whether autoreactive B cells can become resting MBCs is uncertain.

Draft Genome Sequence of Delftia tsuruhatensis Strain 45.2.2, Colonizer of Zebrafish, Danio rerio, Skin Mucus.

Delftia tsuruhatensis strain 45.2.2 is a member of the zebrafish, Danio rerio, skin mucus microbiota.

Draft Genome of Strain JM16, Isolated from Skin Mucus of Zebrafish (Danio rerio).

Acidovorax kalamii strain JM16 was isolated from the skin mucus of the zebrafish, Danio rerio. Its genome is 5.3 Mb with a 65.

Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.

In lupus, Toll-like receptor 7 (TLR7) and TLR9 mediate loss of tolerance to RNA and DNA, respectively. Yet, TLR7 promotes disease, while TLR9 protects from disease, implying differences in signaling. To dissect this 'TLR paradox', we generated two TLR9 point mutants (lacking either ligand (TLR9) or MyD88 (TLR9) binding) in lupus-prone MRL/lpr mice.

Spatial and Seasonal Patterns of the Mosquito Community in Central Oklahoma.

Mosquitoes () are ubiquitous flying insects that function as vectors for several viruses that cause disease in humans. Mosquito abundance and diversity are influenced by landscape features and environmental factors such as temperature and precipitation and vary across seasons and years. The range and phenology of many mosquito species that vector viruses relevant to human health are changing.

IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Infection.

Tuberculosis (TB), caused by , continues to be a major global health problem. Lung granulomas are organized structures of host immune cells that function to contain the bacteria. Cytokine expression is a critical component of the protective immune response, but inappropriate cytokine expression can exacerbate TB.

Genome Sequences of Cluster G Mycobacteriophages Cambiare, FlagStaff, and MOOREtheMARYer.

Mycobacteriophages Cambiare, FlagStaff, and MOOREtheMARYer are newly isolated phages of Mycobacterium smegmatis mc(2) 155 recovered from soil samples in Pittsburgh, PA. All three genomes are closely related to cluster G mycobacteriophages but differ sufficiently in nucleotide sequence and gene content to warrant division of cluster G into several subclusters.