Publications by authors named "Kayla Kim"
Article Synopsis
- The study explores the potential of using stem cell-derived smooth muscle cells (pSMCs) to restore vaginal function following surgical injury, addressing the issue of vaginal prolapse recurrence in women.* ! -
- In experiments with immunocompromised RNU rats, the team injected pSMCs into groups that underwent surgery, and evaluated vaginas after 10 weeks for muscle contraction and tissue health.* ! -
- Results indicated that the group receiving pSMCs showed significantly improved vaginal smooth muscle contractions and collagen production compared to the control group, suggesting the viability of pSMCs for therapeutic applications.* !
Background: Stem-cell-derived therapy is a promising option for tissue regeneration. Human iPSC-derived progenitors of smooth muscle cells (pSMCs) have limited proliferation and differentiation, which may minimize the risk of tumor formation while restoring smooth muscle cell deficiencies. Up to 30 % of women who suffer from recurrence of vaginal prolapse after prolapse surgery are faced with reoperation.
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