Publications by authors named "Kayacan S"

Background: Examining factors affecting nursing care is vital for enhancing practices, improving care quality, and achieving desired patient outcomes.

Aim: To explore emergency nurses' perceptions of care quality, compassion fatigue and conscience stress levels; and evaluate the mediating role of conscience stress between compassion fatigue and perception of nursing care quality.

Methods: This cross-sectional and descriptive study was conducted between April 1 and September 1, 2022, with 384 nurses working in emergency departments across Turkey.

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This study sets out to develop a psycho-social model for assessing the effectiveness of spiritually oriented logotherapy for earthquake victims with PTSD following the 6 February 2023, Kahramanmaraş earthquake in Turkey. The findings of this study will undoubtedly contribute to the development of post-disaster spiritual support services. We developed and implemented a six-week "Psycho-Social Training Programme through Spiritually Oriented Meaning" in the cities of Malatya, Elazığ and Kahramanmaraş, which were significantly affected by the earthquake.

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Background The need for blood arising from illness, surgery, and accidents is met through donations. With global population growth, both non-governmental organizations and public institutions are vital for blood supply and distribution. The Turkish Red Crescent, a leading non-governmental organization in blood donation and humanitarian aid, excels in both national and international contexts, ensuring a safe blood supply and reinforcing social solidarity during crises.

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Exopolysaccharide (EPS) producing Lactic Acid Bacteria (LAB) species can be presented in distinct environments. In this study, Turkish fermented sausage (sucuk) was tested for the presence of EPS producer LAB strains and slimy-mucoid colonies were selected for further tests. Among the isolates, Weissella confusa strain S6 was identified and tested for the physicochemical characterisation of its EPS.

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  • This study isolated and identified distinct strains of lactic acid bacteria from traditional Turkish yogurts using 16S rRNA sequencing and MLST analysis, leading to 14 and 6 unique strains, respectively.
  • The lactic acid production was higher in the identified strains compared to other strains, and their EPS composition primarily featured glucose and galactose, highlighting their potential for food industry applications.
  • Most strains showed strong auto-aggregation and high cell surface hydrophobicity, with some showing antibiotic resistance to gentamicin and kanamycin, indicating their functional properties for industrial use.
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Background: During the pandemic process, nursing care has gained more importance. So, it is critical to evaluate the level of trust in nurses and the perception of care in terms of the patient, in order to improve the care service provided, to achieve the desired successful patient results, to ensure patient satisfaction in nursing care and to create a healthy society in the long term.

Aim: This study aimed to examine the relationship between the level of trust in nurses, care perceptions of patients receiving care with the diagnosis of Covid-19, and the level of trust in nurses and care quality perceptions of patients.

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The yolk-free mayonnaise was formed by Pickering emulsions stabilized by free and encapsulated olive pomace extracts (OPEs) in rocket seed [rocket seed gum nanoparticle (RSGNP)] and chia seed gum nanoparticles at different nanoparticle concentrations. The yolk-free mayonnaise and the control mayonnaise samples were compared in terms of appearance, microstructural, droplet size, emulsion stability, rheological, oxidative stability, and sensory properties. The droplet size decreased by increasing the nanoparticle concentration in yolk-free mayonnaise samples.

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Background/aim: We aimed to investigate the synergistic effects of apigenin and curcumin on the cross-talk between apoptosis and autophagic cell death, as well as on paraptosis in HeLa cells.

Materials And Methods: Cell viability was measured using the MTT assay. Synergistic effects were measured using the Bliss independence model.

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This study aimed to investigate the effect of different drying methods, namely ultrasound-assisted vacuum drying (USV), vacuum drying (VD), and freeze-drying (FD), on the drying kinetics and some quality parameters of dried minced meat. In this study, USV was for the first time applied to the drying of minced meat. The USV and VD methods were conducted at 25 °C, 35 °C, and 45 °C.

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We investigated the cytotoxic and apoptotic effects of a methanol extract of Centaurea nerimaniae, a plant endemic in Turkey, on HeLa and MDA-MB-231 cells. Eight concentrations of C. nerimaniae extract were applied to cells, and cytotoxic effects were measured using the xCELLigence system.

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Article Synopsis
  • The study investigates the anticancer potential of Colchicum baytopiorum, a plant native to Turkey, focusing on its effects on HeLa cancer cells through apoptosis and autophagy.
  • Results indicate that treatment with the plant extract significantly boosts the expression of genes related to both apoptotic and autophagic processes, suggesting an interplay between the two cell death pathways.
  • The findings propose that C. baytopiorum could be a viable new option in cancer therapy, supporting its use in developing anticancer agents.
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Multiple myeloma is a neoplastic plasma cell disorder. It is characterized by collections of abnormal plasma cells accumulating in the bone marrow, where they interfere with the production of normal blood cells. It usually presents as a multisystemic involvement, whose symptoms and signs vary greatly.

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A 43-year old male patient with hyponatremic hypertensive syndrome was diagnosed as catastrophic primary antiphospholipid syndrome (PAPS). He subsequently developed hepatosplenomegaly. The patient also carried thrombophilia- and haemochromatosis-associated gene mutations.

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Background/aims: Diagnosis of spontaneous bacterial peritonitis in cirrhotic ascites is based on a polymorphonuclear leukocyte count of ascitic fluid equal or greater than 250/mm3 in the presence of clinical signs. There is a small number of patients with positive ascitic fluid culture whose polymorphonuclear leukocyte count is less than 250/mm3. In this study, we assessed the diagnostic value of serum high sensitivity C-reactive protein in spontaneous bacterial peritonitis with nonneutrocytic ascites.

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Article Synopsis
  • A 43-year-old woman was hospitalized due to symptoms of abdominal pain and diagnosed with pancytopenia, leading to further examination.
  • During her evaluation, spleen enlargement (splenomegaly) and a significant lesion were identified via CT scan, prompting a splenectomy due to concerns about possible hematologic malignancy.
  • The post-surgery analysis revealed an inflammatory pseudotumor with fibrous tissue and various immune cells, and the patient's condition improved significantly over a two-year follow-up, leaving her healthy and symptom-free.
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  • The study examined the impact of three magnesium dosing regimens on anesthesia and pain management in women undergoing gynaecological surgery.
  • Magnesium groups required significantly less propofol and atracurium compared to the control group, leading to lowered morphine use post-surgery.
  • The findings suggest that a magnesium bolus followed by a lower continuous infusion reduces the need for anesthetics without additional benefits from higher doses, while also affecting heart rates.
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  • The study investigated how various risk factors like high blood sugar, high blood pressure, high cholesterol, and high uric acid affect damage to blood vessels in diabetic patients.
  • It involved 61 patients, primarily with type 2 diabetes, measuring endothelial damage using von Willebrand factor levels.
  • The findings revealed that while controlling diabetes alone didn’t significantly reduce endothelial damage, managing hypertension along with diabetes did lead to notable improvements in blood vessel health.
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Endothelial dysfunction is of vital importance, as it may cause ischemia and dysfunction in various organs. Despite, this problem has been well documented in patients with end-stage renal disease (ESRD), there is not enough data considering this issue following renal transplantation. One of the potential causes of endothelial dysfunction in renal transplant recipients may be administration of calcineurin inhibitors.

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Background: In this prospective-controlled study, we aimed to investigate the effect of changes in insulin resistance and anthropometrical parameters on serum leptin levels (SLL) after renal transplantation (Tx).

Patients And Methods: Thirty-four patients (M/F: 19/15, mean age: 29 +/- 9 yr) and 30 age and sex-matched healthy controls (C) were included. Body weight, subscapular, suprailiac, periumbilical, biceps and triceps skinfold thicknesses, neck, wrist, hip and waist circumferences, as well as body mass index and body fat mass were measured as anthropometrical parameters.

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  • The study investigates the effects of doxazosin and amlodipine on insulin resistance (IR) in patients with chronic renal failure (CRF).
  • Fifteen patients with CRF and nine healthy controls were evaluated, with follow-up over 12 weeks.
  • Results showed that doxazosin significantly reduced IR and fasting insulin levels in CRF patients, unlike amlodipine, indicating that doxazosin could be beneficial for managing hypertension and IR in this population.
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  • The study aimed to assess how the duration of entrapment under rubble affected the health outcomes of crush-syndrome patients after the 1999 Marmara earthquake.
  • The observational analysis included 539 patients from 35 hospitals, revealing an average entrapment time of 11.7 hours, with the majority rescued within 48 hours.
  • Results indicated that longer time under the rubble was associated with more amputations and specific lab results but unexpectedly did not adversely impact survival or kidney function in patients.
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  • PTDM is a common complication after renal transplantation, and its development may be influenced by factors like age, family history of diabetes, and HCV infection.
  • In a study comparing 43 renal transplant patients with PTDM to 43 without, older age, family history of diabetes, and higher rates of HCV were significantly more prevalent in those with PTDM.
  • The presence of pancreatic autoantibodies was similar in both groups, indicating that non-immunologic factors, particularly HCV infection, may play a substantial role in the development of PTDM.
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  • Chronic allograft dysfunction (CAD) is the main reason for kidney transplant failure, influenced by immunological and non-immunological factors, with a specific focus on the renin-angiotensin system and ACE gene polymorphism.
  • A study involving 143 renal transplant recipients from living donors found that 28% experienced CAD, with higher donor age, hypertension, and serum uric acid levels correlating with CAD, but not ACE genotype.
  • The findings suggest that donor age, hypertension, and uric acid levels are significant risk factors for CAD, while the ACE genotype of either donors or recipients does not impact CAD development.
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  • Many patients with end-stage renal disease seek commercial transplants in Third World countries due to a lack of available organs, despite known risks and ethical concerns.
  • A study analyzed the outcomes of 115 patients who received commercial transplants between 1992 and 1999, revealing a high rate of complications, including rare infections.
  • While patient survival rates for commercial transplants were similar to those from living related transplants, graft survival rates were significantly lower, indicating the risks associated with commercial transplantation.
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