Comparative Study of Clinical Severity and Biochemical Markers in Pre COVID-19 and COVID-19 Rhino-Orbito Cerebral Mucormycosis.

In view of high surge of sinonasal mucormycosis cases after the second wave of covid 19, present study was planned to know and compare the clinical severity of the disease and also to better understand the difference in the biochemical markers during precovid and post covid period. This retrospective observational study included all cases of sinonasal mucormycosis which were treated in our institute from August 2012 to August 2021. Details of these cases were collected from hospital database system.

A Novel Teaching-Learning Method of Utilizing Ultrasonography as a Tool to Enhance Clinical Examination Skills of House Surgeons in Evaluating Cervical Lymph Nodes.

Aim: A study was conducted to ascertain if ultrasonography assisted learning facilitates the House Surgeons to enhance their clinical skill of identifying enlarged cervical lymph nodes.

Materials And Methods: A prospective, cross-sectional analytical study was conducted in the in a Medical College for 6 months from May to October 2021. It included 50 house surgeons posted to the department of ENT on rotation and patients with one or more enlarged cervical lymph nodes.

Morphometry around Cochleostomy Site to Aid Safe Cochlear Implantation.

Introduction: In morphologically normal-appearing inner ears, measurements of the distance between the round window and carotid canal (RCD), the maximum diameter of the basal turn of the cochlea next to the round window (BD), and the thickness of the promontory (PT) just lateral to the basal turn may be used as guide for safe cochleostomy and implant placement.

Materials And Methods: From January to March 2022, a cross-sectional observational study was carried out in a tertiary care hospital. The round window to carotid canal distance (RCD), the largest diameter of the cochlea's basal turn next to the round window (BD), and the thickness of the promontory immediately lateral to the basal turn (PT) were measured using CT temporal bone images of 150 persons without cochlear abnormalities.

Estimation of Normal Semi-circular Canal Dimensions on Computed Tomography.

Aims: To measure and compare length, width and luminal diameters of semi-circular canals (SCC) on Multiplanar reformatted CT images in individuals without any features of vestibular dysfunction.

Materials And Methods: A prospective, cross sectional, observational study was conducted in a tertiary care hospital in October - November 2021. Multiplanar reformatted CT temporal bone images of 50 participants without features of vestibular dysfunction were used to measure the curved lengths, widths and luminal diameters of the three semi-circular canals.

Anti-inflammatory and preventive activity of white mulberry root bark extract in an experimental model of pancreatitis.

Pancreatitis is characterized by highly morbid inflammation in the pancreas. Currently, there is no specific drug available for pancreatitis except supportive medicines. The present study assessed the pancreato-protective effect of root bark extract by using alcohol and cerulein-induced model of pancreatitis.

Doppler indices of superior thyroid artery in clinically euthyroid adults.

Context: Ultrasonography of thyroid gland is a frequently performed investigation. Many of the diffuse thyroid pathologies are associated with altered vascularity. In view of potential applications and scant available data, there is a need to find normal values of Doppler indices of superior thyroid artery (STA).

A Study of Effect of Consanguinity on Cochlear Morphology in Patients with Congenital Bilateral Profound Sensorineural Hearing Loss.

Consanguinity has been considered as one of the risk factors predisposing to the development of congenital hearing loss. Effect of consanguinity on cochlear morphology has been subject of speculation, though many studies have provided insight into functional aspect of cochlea. This study was conducted to know the effect of consanguinity on cochlear morphology, if any.

Application of Curved MPR Algorithm to High Resolution 3 Dimensional T2 Weighted CISS Images for Virtual Uncoiling of Membranous Cochlea as an Aid for Cochlear Morphometry.

Introduction: With the use of various surgical techniques, types of implants, the preoperative assessment of cochlear dimensions is becoming increasingly relevant prior to cochlear implantation. High resolution CISS protocol MRI gives a better assessment of membranous cochlea, cochlear nerve, and membranous labyrinth. Curved Multiplanar Reconstruction (MPR) algorithm provides better images that can be used for measuring dimensions of membranous cochlea.

Replication of Japanese encephalitis virus in mouse brain induces alterations in lymphocyte response.

The experimental model using intracerebral (i.c.) challenge was employed in many studies evaluating the protection against disease induced by Japanese encephalitis virus (JEV).

Induction of MHC-I and thymic depletion due to replication of JEV in mouse brain.

The thymus is a primary lymphoid organ that is responsible for T cell development and maturation. Thymic depletion accompanied by apoptosis and altered T cell maturation occurs during several viral infections. Here we show that adult mice intracerebrally infected with Japanese encephalitis virus exhibit severe cell depletion and alterations in the CD4(+) and CD8(+) single as well as CD4(+)CD8(+) double positive cell populations.