A Simple Selective Probe for Lysine Detection in Tablets, Food Samples and Cells.

A novel probe ITQ (9-(((E)-1 H-inden-1-ylidene)methyl)-8-(3-(((E)-1 H-inden-1-ylidene)methyl)phenoxy)-2,3,6,7-tetrahydro-1 H,5 H-pyrido[3,2,1ij]quinolone) was successfully designed and synthesized to detect amino acid lysine (Lys). The selective sensing behavior of the probe ITQ was observed using absorption and emission spectral results. Further, the probe ITQ exhibits a strong binding affinity for Lys [1.

A Reversible Fluorescent Chemosensor for the Selective Detection of Cu and CN ions by Displacement Approach.

A novel fluorescence chemosensor BDP (2-(1-(benzothiazol-2-yl)-5-(4-(diphenylamino)phenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenol) has been synthesized and its sensing behavior has been screened towards various cations by absorption, emission and mass spectroscopic techniques. The probe BDP detects Cu ions preferentially over other metal ions, and the resulting BDP-Cu ensemble acts as a secondary sensor for cyanide anion detection over other anions. The fluorescence intensity of the probe BDP is quenched when it comes into contact with Cu ions, but it is increased reversibly when it comes into contact with cyanide anion, according to spectroscopic measurements.

A new nitrile vinyl linked ultrafast receptor to track cyanide ions: Utilization on realistic samples and HeLa cell imaging.

A simple D - A (donor - acceptor) type receptor ((2E, 2'E)-3, 3'-(10-octyl-10H-phenothiazine-3,7-diyl)bis(2-(benzo[d]thiazol-2-yl)acrylonitrile)) (PBTA) containing nitrile-vinyl linkage was designed and completely characterized. The receptor PBTA detects CN ions based on "turn-off" effect with admirable spectral properties. It also owns some of the merits like "naked-eye" color change, ultrafast response (90 s), lowest detection limit (1.

An aqueous mediated ultrasensitive facile probe incorporated with acrylate moiety to monitor cysteine in food samples and live cells.

A colorimetric probe TQA ((E)-4-(((8-(sec-butoxy)-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)methylene)amino)benzylacrylate) possessing greater potent towards the sensing of cysteine was successfully synthesized and characterized. The aqueous soluble probe TQA detects Cys based on "ON-OFF" effect with excellent absorbance and emission properties. The probe TQA detects Cys up to its ultra-low level concentration of 1.

Design of a dual responsive receptor with oxochromane hydrazide moiety to monitor toxic Hg and Cd ions: Usage on real samples and live cells.

In this work, we report a facile receptor OMB [N',N"'-(3-((4-oxochroman-3-yl)methylene)pentane-2,4- diylidene)bis(4-methoxybenzohydrazide)] for the simultaneous detection of toxic analytes (Hg and Cd ions) in environment and biological samples. The receptor OMB exhibits an excellent selectivity and sensitivity which was determined using absorption and emission spectra. The receptor OMB shows rapid detection with lowest LOD (0.

Dinitrobenzene ether reactive turn-on fluorescence probes for the selective detection of HS.

Two novel fluorescent probes, namely, 3-(2,4-dinitrophenoxy)-2-(4-(diphenylamino)phenyl)-4-chromen-4-one (P1) and 3-(2,4-dinitrophenoxy)-2-(pyren-1-yl)-4-chromen-4-one (P2), were designed and synthesized here. The probes (P1 and P2) were found to be highly selective and sensitive toward hydrogen sulfide (HS) in the presence of a wide range of anions. The new probes (P1 and P2) were fully characterized by analytical, NMR spectroscopy (H and C), and ESI mass spectrometry.

A bisphenol based fluorescence chemosensor for the selective detection of Zn and PPi ions and its bioluminescence imaging.

A bisphenol based fluorescence "turn-on" chemosensor 4,4'-(propane-2,2-diyl)bis(2-((E)-(2-(benzo[d]thiazol-2-yl)hydrazineyldene)methyl)phenol) (BHMP) has been synthesized and its sensing behavior was tested towards various ionic species. The chemo-sensing behavior of BHMP has been established through absorption, fluorescence, NMR, and mass spectroscopic techniques. The probe BHMP selectively detects zinc ions over other metal ions and the resulting BHMP + Zn ensemble serves as a secondary probe for the detection of pyrophosphate (PPi) anion specifically over other anions.

A novel ratiometric fluorescent probe for "naked-eye" detection of sulfite ion: Applications in detection of biological SO ions in food and live cells.

A new "turn-on" luminescent probe PI has been designed and synthesized for the selective detection of sulfite ions based on the mechanism of nucleophilic addition. The designed probe PI owns naked eye detection, excellent selectivity, sensitivity, rapid response (150 s) and low limits of detection (LOD) of 0.57 μM, which is an agreeable limit by the world wide expert food additive committees.

Persistent unilateral nictitating membrane in a 9-year-old girl: A rare case report.

We report a case of persisting nictitating membrane in a 9-year-old girl presenting to us with the complaints of fleshy mass in the medial part of the left eye since birth, which was nonprogressive. On examination, her left eye was amblyopic with a vision of 20/500. The membrane was continuous with the medial canthus and was spread in a horizontal fashion, covering the underlying bulbar conjunctiva and one-third of the cornea.