Assessing the role of Osteopontin in prognosis of oral squamous cell carcinoma- A systematic review.

Background: Oral cancer is always a global burden. It is the sixteenth most common cancer. It leads to metastasis since it is often diagnosed at late stages.

Identification of a novel bacterium in high caries risk adolescence: A metagenomic and melt curve analysis.

Background: which comprise only 2% have long been presumed to be the specific pathogen responsible for caries. A novel caries associated bacterium namely is recognized to be ecologically competitive in active caries lesions. The actual pathogen needs to be identified, so as to specifically target and reduce the prevalence of caries in a given community.

Fracture Resistance of Endodontically Treated Premolars Restored with Flowable Short Fibre-Reinforced Resin Composite-An In Vitro Study.

Objective: This in vitro study aimed to evaluate the fracture resistance of endodontically treated premolar teeth restored with flowable short fibre-reinforced resin composite (FSFRRC) at varying depths within the root canals.

Methods: Fifty freshly extracted human single-rooted premolars were divided into 5 Groups (n=10), Group I (IN) intact teeth, Group II (P) restored coronally with resin composite only, Group III, IV and V (FSFRRC2, FSFRRC4, FSFRRC6) based on post space preparation to the respective depths of 2, 4 and 6 mm. Root canal treatment was performed for all the samples of Group II, III, IV, V and the teeth were decoronated 2 mm above cementoenamel junction.

The evaluation of cytotoxicity and cytokine IL-6 production of root canal sealers with and without the incorporation of simvastatin: an invitro study.

Background: Freshly mixed root canal sealers when proximate the periapical tissues, trigger varying degrees of cytotoxicity/inflammatory reactions. Simvastatin, a class of the drug statin, is a widely used cholesterol-lowering agent with additional anti-inflammatory activities. This study assessed the effects of simvastatin on cytotoxicity and the release of IL-6 (Interleukin-6) production when incorporated in zinc oxide eugenol and methacrylate resin-based sealers.

Fracture Resistance of Endodontically Treated Teeth Restored with 2 Different Fiber-reinforced Composite and 2 Conventional Composite Resin Core Buildup Materials: An In Vitro Study.

Introduction: The purpose of this in vitro study was to comparatively evaluate the fracture resistance of endodontically treated teeth restored with 2 fiber-reinforced composite resins and 2 conventional composite resin core buildup materials.

Methods: Sixty noncarious unrestored human maxillary premolars were collected, endodontically treated (except group 1, negative control), and randomly divided into 5 groups (n = 10). Group 2 was the positive control.

Effect of Green and White Tea Pretreatment on Remineralization of Demineralized Dentin by CPP-ACFP-An Invitro Microhardness Analysis.

Introduction: Mechanical performance of dentine is of major significance for the overall function of the teeth. Remineralization of carious dentine is the ultimate goal in re-establishing the functionality of the affected tissue so as to regain and maintain the mechanical properties of dentine. Functional remineralization of the affected dentin involves stabilization of both inorganic and organic component, but Caesin Phosphopeptide Amorphous Calcium Flurophosphate (CPP-ACFP) stabilizes only inorganic content.

Effect of various antioxidants on the shear bond strength of composite resin to bleached enamel: An in vitro study.

Objective: The aim of this in vitro study was to evaluate and compare the effect of 10% sodium ascorbate, 6.5% proanthocyanidin, and 5% lycopene on the bond strength of composite resin to bleached enamel.

Materials And Methods: Labial enamel surfaces of 100 extracted human maxillary central incisors were used in this study.

Effect of bleaching with two different concentrations of hydrogen peroxide containing sweet potato extract as an additive on human enamel: An in vitro spectrophotometric and scanning electron microscopy analysis.

Objectives: To evaluate the color change in teeth bleached with two different concentrations of hydrogen peroxide, containing sweet potato extract as an additive, using a spectrophotometer, and to evaluate the surface changes in enamel using a scanning electron microscope (SEM).

Materials And Methods: Baseline color values of 24 artificially stained incisors were obtained using a spectrophotometer. The specimens were divided into two groups of 12 teeth, each based on the concentration of hydrogen peroxide (H(2)O(2)) as follows: Group I - 35% H(2)O(2) and Group II - 10% H(2)O(2).

Degree of conversion of two dentin bonding agents with and without a desensitizing agent using fourier transform infrared spectroscopy: An in vitro study.

Objective: This in vitro study investigated the effect of a desensitizer on the degree of conversion of two bonding resins using Fourier transform infrared (FTIR) spectroscopy.

Materials And Methods: An etch-and-rise bonding resin and a self-etching adhesive resin were selected for the study. Vivasens (Ivoclar Vivadent) was used as a desensitizing agent.

An in vitro evaluation of the effect of deep dry cryotreatment on the cutting efficiency of three rotary nickel titanium instruments.

Context: Cryogenic methods have been used to increase the strength of metals.

Aim: The aim of this study was to evaluate the effect of deep dry cryotherapy on the cyclic fatigue resistance of rotary nickel titanium instruments.

Materials And Methods: Twenty K3, RaCe and Hero Shaper nickel titanium instruments, size 25, 0.

Ultramorphological characterization of the resin dentin interface--an in vitro analysis of nanoleakage patterns of dentin adhesives.

Aim And Design: The requirements of an effective dentin adhesive system include the ability to thoroughly infiltrate the collagen network and partially demineralized zone, to encapsulate the collagen and hydroxyapatite crystallites, to produce a well polymerized durable hybrid layer with high bond strengths. Microleak-age and marginal percolation are the most detrimental factors thwarting the success of any restoration. However the presence of leakage pathways, called nanoleakage have been observed in the hybrid layer, even in the absence of microleakage.

Duration-dependent susceptibility of endodontic pathogens to calcium hydroxide and chlorhexidene gel used as intracanal medicament: an in vitro evaluation.

The aim of this study was to evaluate the effective duration of antimicrobial activity of a calcium hydroxide-based medicament (Apex Cal) and 2% chlorhexidene gluconate gel against selected endodontic pathogens (Enterococcus faecalis, Candida albicans, Porphyromonas gingivalis, and Prevotella intermedia). The agar diffusion test was used to determine the antimicrobial activity. Chlorhexidene gluconate gel showed the largest inhibitory zones.

Influence of irrigating needle-tip designs in removing bacteria inoculated into instrumented root canals measured using single-tube luminometer.

This study tested the mechanical efficacy of various irrigating needle tip designs on bacteria inoculated into instrumented root canals. Root canals of 30 extracted permanent canines were prepared to size 60 at working length (WL) using ProFile 0.04 taper rotary nickel-titanium files.