Lactic acid (LA) is a nifty molecule with an eclectic range of applications in innumerable industries and is produced through biological and chemical processes. Factually, LA is converted into lactide (LAC), which is the precursor for polylactic acid (PLA). PLA is considered one of the first-rate replacements for petroleum-based products and is believed to be environmentally sustainable.
View Article and Find Full Text PDFLactic acid is a versatile, multi-functional organic monomer in various industries, creating worldwide demand. High titer lactic acid production was achieved by novel J2V2AA through sugarcane molasses fermentation up to 178 mg mL. A metabolomics approach such as combined GC-MS and LC-MS was applied to elucidate the involvement of key metabolites in lactic acid production.
View Article and Find Full Text PDFRanipet is an industrial hub located 120 km away from Chennai houses around 250 tanneries beside other industries. Tanneries and Tamil Nadu Chromate and Chemicals Limited (TCCL) generated and dumped tons of chromium waste on land and water bodies which is the major threat to the people living in the area for several years. In this study, heavy metal pollution in Ranipet industrial zone was estimated using the Heavy Metal Pollution Index (HPI) model along with spatial distribution maps.
View Article and Find Full Text PDFHydrogels are 3D crosslinking networks of hydrophilic biopolymers which can able to absorb and retain large amount of water. In this present study, the Sodium alginate (SA)- Galactoxyloglucan (GXG) blended hydrogel beads were prepared and optimized through two level optimization steps. Alginate and xyloglucan are the cell wall polysaccharides biopolymers obtained from the plant sources, Sargassum sp.
View Article and Find Full Text PDFThe results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ethyl acetate extract of P.
View Article and Find Full Text PDFLactic acid bacteria (LAB) have the potential to degrade intestinal oxalate and this is increasingly being studied as a promising probiotic solution to manage kidney stone disease. In this study, oxalate degrading LAB were isolated from human faeces and south Indian fermented foods, subsequently assessed for potential probiotic property in vitro and in vivo. Based on preliminary characteristics, 251 out of 673 bacterial isolates were identified as LAB.
View Article and Find Full Text PDFAs the use of various anticancer drugs is associated with many undesirable side effects, there is an urgent need for the discovery of new, better, and specific anticancer compounds. Antioxidant and antiproliferative activities as well as effects on cell morphology were investigated for methanol (M), chloroform (C), ethyl acetate (E), and aqueous (A) extracts of Caulerpa peltata, Gelidiella acerosa, Padina gymnospora, and Sargassum wightii using 2,2-diphenyl-1-picrylhydrazyl radical-scavenging, ferrous ion chelation, and resazurin-based growth inhibition (in A549, HCT-15, MG-63, and PC-3 cell lines) assays. A general trend was the greater extraction of phenols and flavonoids by chloroform and ethyl acetate, which showed higher activity in many assays.
View Article and Find Full Text PDFSynonymous codon usage of 53 protein coding genes in chloroplast genome of Coffea arabica was analyzed for the first time to find out the possible factors contributing codon bias. All preferred synonymous codons were found to use A/T ending codons as chloroplast genomes are rich in AT. No difference in preference for preferred codons was observed in any of the two strands, viz.
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